About: Combined chemical and enzymatic synthesis of complex multivalent glycoconjungates - ways to new materials and glycodrugs     Goto   Sponge   NotDistinct   Permalink

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Description
  • preparation of glykomimetics, mainly based on polyaminoamidodendrimers (PAMAM) and kalixarens and elaborate procedure of enzyme modification (en)
  • příprava glykomimetik na bázi polyaminoamido dendrimerů (PAMAM) a kalixarenů a vypracovat metodiku enzymových modifikací
Title
  • Combined chemical and enzymatic synthesis of complex multivalent glycoconjungates - ways to new materials and glycodrugs (en)
  • Kombinovaná chemická a enzymová syntéza komplexních multivalentních glykokonjugátů – cesty k novým materiálům a glykoterapeutikům.
skos:notation
  • OC 136
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  • Combined chemical and enzymatic synthesis; complex multivalent glycoconjungates; new materials and glycodrugs; enzyme modification (en)
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  • %22New glycosylazide donor for glycosidases was developed. Extensive multivalent ligand optimizations for antitumor NK cell activation void of apoptotic effects - these ligands have potential to pass to the preclinical testing.%22 (en)
  • %22Byl vyvinut nový glykosylazidový donor pro glykosidasy a provedena optimalizace multivalentních ligadů pro aktivaci protinádorových NK buněk se zamezením následné apoptosy - tyto ligandy nové generace mají potenciál postoupit do předklinických testů.%22 (cs)
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  • complex multivalent glycoconjungates
  • new materials and glycodrugs
  • Combined chemical and enzymatic synthesis
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