About: Ischaemia - reperfusion injury and hemodynamics in porcine model of ruptured abdominal aorta aneurysm     Goto   Sponge   NotDistinct   Permalink

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Description
  • The development of clinically relevant porcine ischemia-reperfusion abdominal aorta aneurysm rupture. Impact on hemodynamics, tissue metabolism, oxidative stress and inflammation activation will be observed. Subsequently, the influence of hyperoxia will be tested. (en)
  • Rozvoj klinicky relevantního prasečího ischemicko-reperfuzního modelu ruptury aneurysmatu břišní aorty. Bude sledováno ovlivnění hemodynamiky, tkáňového metabolismu, oxidačního stresu a aktivace zánětu. Následně bude ukoumána možnost ovlivnění pomocí hyperoxie.
Title
  • Ischaemia - reperfusion injury and hemodynamics in porcine model of ruptured abdominal aorta aneurysm (en)
  • Prasečí model ruptury aneurysmatu abdominální aorty. Vliv časování hyperoxie na parametry inflamace a ischemicko-reperfuzního traumatu
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  • NS10109
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  • ichemia; reperfusion; hemorrhage; pig; anerysm; shock (en)
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  • Byl validován komplexní prasečí model simulující léčbu ruptury aneurysmatu břišní aorty (rAAA). Hyperoxie aplikovaná dlouhodobě v perioperačním období měla jen malý ekekt na průběh rAAA (cs)
  • A comprehensive pig model of ruptured abdominal aortic aneurysm repair (rAAA) was validated. Hyperoxia given for the prolonged perioperative period had only minor effects on the clinical course of rAAA. (en)
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  • pig
  • reperfusion
  • anerysm
  • hemorrhage
  • ichemia
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