About: Inter- and intracellular signal systems

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=KSK2038602
Description	The project is running at Inst. Mol. Genet., Inst. Aminal Physiol. Genet., Inst. Exper. Botany and Inst. Plant Mol. Biol. and is dealing with: a/ molecular mechanisms of signal transduction from surface structures into mammalian cells and its significance for cell differentiation, tumor transformation, fertilization and immune response, b/ signals determining molecular and cellular bases of gametogenesis, of fertilization and early embryo development, c/ signalling systems in differentiation and development of plant cells, organs and whole plants and their response to environmental conditions, d/ signals initiating defence mechanisms of plant photosynthetic apparatus to photoinhibition, photodestruction and other stresses. The results obtained will contribute to better knowledge of interdependence of signalling pathways and may lead also to formulation of rational approaches in therapy of some human diseases and higher effectiveness of breeding programmes. (en) Projekt, řešený na 4 pracovištích AV (ÚMG, ÚŽFG, ÚEB a ÚMBR), je zaměřen na studium a/ molekulárních mechanismů přenosu signálů z povrchových struktur do nitra savčích buněk a jejich význam pro buněčnou diferenciaci, nádorovou transformaci, fertilizaci a imunitní odpověď, b/ signálů určujících molekulární a buněčné základy gametogeneze, procesu oplození a časného embryonálního vývoje obratlovců, c/ signálních systémů v řízení diferenciace a vývoje rostlinných buněk, orgánů a celistvých rostlin a jejichreakcí na podmínky prostředí, d/ signálů, iniciujících ochranné mechanismy fotosyntetického aparátu rostlin před fotoinhibicí, fotodestrukcí a jinými stresy. Získané výsledky přispějí k lepšímu poznání vzájemné souvislosti signalizačních drah a mohou vést i k fomulaci racionálních přístupů v terapii některých lidských chorob, medicinských technik a zefektivnit programy šlechtění rostlin a živočichů.
Title	Inter- and intracellular signal systems (en) Soustava vnitrobuněčných a mezibuněčných signálů
skos:notation	KSK2038602
http://linked.open...avai/cep/aktivita	Scheme of the development of investigative research in key branches of science
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/KSK2038602/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/KSK2038602/celkoveNaklady
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	597615
http://linked.open...ai/cep/hlavniObor	EB - Genetika a molekulární biologie
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...ep/partnetrHlavni	Ústav experimentální botaniky AV ČR, v.v.i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	38 (xsd:int)
http://linked.open...enychVysledkuVRIV	38 (xsd:int)
http://linked.open...iciPoslednihoRoku	2001
http://linked.open...atUdajeProjZameru	2001
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open.../cep/vedlejsiObor	CE - Biochemie ED - Fyziologie
http://linked.open...jektu+dodavatelem	Řešení projektu přineslo důležité poznatky především v oblasti poznávání mechanizmů přenosu vnitrobuněčných i mezibuněčných signálů u živočichů i rostlin. (cs)
http://linked.open...tniCyklusProjektu	ZBBBKU
is http://linked.open...vavai/riv/projekt of	Determination of the complete covalent structure of the major glycoform of DQH sperm surface protein, a novel trypsin-resistant boar seminal plasma O-glycoprotein related to pBl protein. Lectin-like properties of boar spermadhesis. Technique of the modulated chlorophyll fluorescence: basic concepts, useful parameters, and some applications. Butyrolactone I Reversibly Inhibits Meiotic Maturation of Bovine Oocytes, Without Influencing Chromosome Condensation Activity. Behaviour of mouse primary spermatocyte nuclei after fusion to enucleated metaphase II oocytes. Culture of bovine oocytes from small antral follicles in meiosis-inhibiting medium with butyrolactone I: RNA synthesis, nucleolar morphology and meiotic competence. Cell cycle synchronization of porcine fetal fibroblasts: Effects of serum deprivation and reversible cell cycle inhibitors. Behavior of M-phase synchronized blastomeres after nuclear transfer in cattle. Bovine seminal ribonuclease exerts selective cytotoxicity toward neuroblastoma cells both sensitive and resistant to chemotherapeutic drugs. The Collection of Oviductal Fluid from Sheep. CDw149 antibodies recognize a clustered subset of CD47 molecules associated with cytoplasmic signaling molecules. Germ-free mice do not develop ankylosing enthesopathy, a spontaneous joint disease. Impact of Two-step In Vitro Culture Systems on Developmental Potency of Oocytes. Fine-structural cytochemical and immunocytochemical observations on nuclear bodies in the bovine 2-cell embryo. Genetic variation in in-vitro cytokine-induced production of nitric oxide by murine peritoneal macrophages. Rearrangement and Loss of Bromine Radical and CO from some Bromobenzyl Alcohols Following Electron Ionisation. Studies of phospholipid binding to N-terminal domain of membrane protein light-harvesting complex II Possibilities of new system for LD/CD measurements in photosynthesis research. Checkpoint control of the G2/M phase transition during the first mitotic cycle in mammalian eggs A MAP kinase is activated late in plant mitosis and becomes localized to the plane of cell division. Changes in activity of glucose-6-phosphate and 6-phosphogluconate dehydrogenase isozymes upon potato virus Y infection in tobacco leaf tissues and protoplasts. Characterization of the human leucocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules. Characterization of Boar Spermadhesins by Monoclonal and Polyclonal Antibodies and Their Role in Binding to Oocytes. Nucleolar Ultrastructure in Bovine Nuclear transfer Embryos. Oviduct Secretion Contributes to the Establishment of Species Specific Barrier Preventing Penetration of Oocytes with Foreign Spermatozoa. Activation of bovine oocytes by specific inhibition of cyclin-dependent kinases. Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells. Cytokinins and water stress. Effect of intraovarian factors on porcine follicular cells: cumulus expansion, granulosa and cumulus cell progesterone production. Developmental regulation of effect of epidermal growth factor on porcine oocyte-cumulus cell complexes: Nuclear maturation, expansion, and F-actin remodeling. D-penicillamine and granulosa cells can effectively extend the fertile life span of bovine frozen-thawed spermatozoa in vitro: Effect on fertilization and polyspermy. Nuclear Gamma-Tubulin during Acentriolar Plant Mitosis. Nuclear .tau.-Tubulin during Acentriolar Plant Mitosis. Phenotypic effects of CD3 targeting into glycosphingolipid-enriched membrane microdomains (GEMs) of T cells. Phenotypic effects of CD3zeta targeting into glycosphingolipid-enriched membrane microdomains (GEMs) of T cells. The shoot apex as a marker of the responsivity to photoperiodic treatment inducing flowering of Chenopodium Rubrum L. Secretion of Paracrine Factors Enabling Expansion of Cumulus Cells Is Developmentally Regulated in Pig Oocytes. Soluble isoforms of CEACAM1 containing the A2 domain increase serum levels in patients with obstructive jaundice and differences in 3-fucosyl-N-acetyl-lactosamine moiety.
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