About: Transcriptional regulatory network(s) controlled by sigma factors in Corynebacterium glutamicum

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About: Transcriptional regulatory network(s) controlled by sigma factors in Corynebacterium glutamicum Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GC204/09/J015
Description	Bacterial sigma factors reversibly bind to the multisubunit core RNA polymerase to constitute a holoenzyme and control the specific transcription initiation from various classes of promoters. The primary sigma factor recognizes the promoters of housekeeping genes whereas alternative sigma factors are involved in growth-dependent transcription and in cell response to exogenous factors, such as heat, osmotic and oxidative stress. The bilateral project is focused on elucidating the roles of the alternative sigma factors in function of individual promoters and in the complex regulatory network controlling gene expression in Corynebacterium glutamicum. The methods of promoter analysis will be combined with global genome analysis used in the German laboratory. Identification of the promoters recognized by alternative sigma factors, assigning the individual promoters to the particular sigma factors, definition of the consensus sequences of the promoter classes and use of the characterized promoters for the construction of controlled expression systems are the main aimes of the Czech team. (en) Cílem projektu je poznat úlohu jednotlivých alternativních sigma faktorů RNA polymerasy při transkripci z různých skupin promotorů, definovat konvenční sekvence těchto tříd promotorů a přispět k vytvoření modelu regulační sítě řízené alternativními sigma faktory u Corynebacterium glutamicum.
Title	Transcriptional regulatory network(s) controlled by sigma factors in Corynebacterium glutamicum (en) Mechanismy regulace transkripce řízené sigma faktory v Corynebacterium glutamicum
skos:notation	GC204/09/J015
http://linked.open...avai/cep/aktivita	International projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GC204%2F09%2FJ015/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GC204%2F09%2FJ015/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-02-09 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	91962010
http://linked.open...ai/cep/hlavniObor	EB - Genetika a molekulární biologie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	Corynebacterium glutamicum; sigma faktory; promotory; regulace genové exprese (en)
http://linked.open...ep/partnetrHlavni	Mikrobiologický ústav AV ČR, v.v.i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	7 (xsd:int)
http://linked.open...enychVysledkuVRIV	7 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-04-16 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/204%2F09%2FJ015
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open.../vavai/cep/soutez	SGA02009GA1GC
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	EI - Biotechnologie a bionika EE - Mikrobiologie, virologie
http://linked.open...ep/zahajeniReseni	2009-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en) Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	Corynebacterium glutamicum promotory sigma faktory
is http://linked.open...vavai/riv/projekt of	Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum Promoters and Plasmid Vectors of Corynebacterium glutamicum Tools for genetic manipulations in Corynebacterium glutamicum and their applications Analysis of Corynebacterium glutamicum Promoters and Their Applications Sigma factors and promoters in Corynebacterium glutamicum Construction of in vitro transcription system for Corynebacterium glutamicum and its use in the recognition of promoters of different classes The role of sigma factor SigH in transcriptional regulation in Corynebacterium glutamicum
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GC204%2F09%2FJ015/2009/ico%3A61388971 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GC204%2F09%2FJ015/2010/ico%3A61388971 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GC204%2F09%2FJ015/2011/ico%3A61388971 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GC204%2F09%2FJ015/2012/ico%3A61388971

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