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| Description
| - The project will study the effect of synthetic inhibitors of polymerases on replication and movement of viruses in plants. The project will be the first assessment of phytotoxicity and antiviral activity of acyclic nucleosid phosphonates (ANPs), PMEA, PMEDAP, PMPA and HPMPC against plant DNA virus (CaMV) and RNA viruses (TYMV, RaMV, TuMV) with different replication mechanisms. The effect of ANPs will be followed on symptom expression, formation of virions and accumulation of viral genomes. The effect of ANPs will be compared with Ribavirin, so far the most efficient and practically used antiviral compound against plant viruses, which will be used as a standard. The project will fill the gap in our knowledge about possible elimination of DNA viruses from plants. The results could be exploited in the production of virus-free vegetatively propagated crops (potato, fruits, grapevine, hops, ornamentals), and virus-free germplasm collections used for crop breeding and protection of biodiversity. (en)
- Vyhodnotit protivirový účinek a fytotoxicitu acyklických nukleosid fosfonátů (PMEA,PMDAP,PMPA a HPMPC) proti rostlinnému dsDNA viru a RNA virům (TYMV,RaMV a TuMV), s rozdílným replikačním mechanismem, v porovnání s Ribavirinem, pomocí nově navrženého in vitro modelu na brukvovitých rostlinách.
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| Title
| - Effect of acyclic nucleosid phosphonates and other antimetabolites against plant viruses (en)
- Účinnost acyklických nukleosid fosfonátů a dalších antimetabolitů proti rostlinným virům
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...hodnoceniProjektu
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - rostlina; virus; acyklické nukleosid fosfonáty; antivirotika (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...lneniVMinulemRoce
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| http://linked.open.../prideleniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...ep/ukonceniReseni
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| http://linked.open.../cep/vedlejsiObor
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| http://linked.open...ep/zahajeniReseni
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| http://linked.open...jektu+dodavatelem
| - The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en)
- Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
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| http://linked.open...tniCyklusProjektu
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| http://linked.open.../cep/klicoveSlovo
| - rostlina
- acyklické nukleosid fosfonáty
- virus
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| is http://linked.open...vavai/riv/projekt
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| is http://linked.open...vavai/cep/projekt
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