About: Regulation of muscle phenotype under normal, experimental and pathological conditions

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About: Regulation of muscle phenotype under normal, experimental and pathological conditions Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GA304/08/0256
Description	In Europe over 300.000 patients suffer from muscular diseases and specific muscle genes and extrinsic factors play a significant role in differentiation of normal and aberrant muscle characteristics. Our model of heterochronous iso-transplantation enables (en) V Evropě více než 300 000 pacientů trpí poruchami funkce svalů a specifické svalové geny a vnější podněty hrají významnou roli v normálním vývoji svalu i při vzniku svalových onemocnění. Náš model heterochronní izotransplantace umožňuje studovat jak časné
Title	Regulation of muscle phenotype under normal, experimental and pathological conditions (en) Regulace svalového fenotypu za normálních, experimentálních a patologických stavů
skos:notation	GA304/08/0256
http://linked.open...avai/cep/aktivita	Standard projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GA304%2F08%2F0256/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GA304%2F08%2F0256/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2014-01-30 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	92539302
http://linked.open...ai/cep/hlavniObor	EA - Morfologické obory a cytologie
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	muscle; phenotype; muscle; transplantation; myosin; heavy; chains; calcium; binding; proteins; human; muscle; diseases (en)
http://linked.open...ep/partnetrHlavni	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	32 (xsd:int)
http://linked.open...enychVysledkuVRIV	32 (xsd:int)
http://linked.open...lneniVMinulemRoce	2012-03-30 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/304%2F08%2F0256
http://linked.open...iciPoslednihoRoku	2012
http://linked.open...atUdajeProjZameru	2013
http://linked.open.../vavai/cep/soutez	SGA02008GA-ST
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2012-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	ED - Fyziologie
http://linked.open...ep/zahajeniReseni	2008-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	Investigators reached a new results on expression, transformation phenotype and function of muscles and heart muscle during differentiation and regeneration. Planed aims were completed, results were presented in 23 papers published in journals with IF, in 8 proceedings articles and 76 congress abstracts with grant dedication. Excellent realization of grant project. (en) Byla dosažena řada nových poznatků týkajících se změn exprese, fenotypu i funkce během diferenciace a regenerace kosterních svalů i srdeční svaloviny. Plánované cíle byly splněny a získané výsledky byly publikovány ve 23 článcích zveřejněných v časopise s IF, 8 článcích zveřejněných ve sbornících a v 76 abstraktech dedikovaných projektu. Splnění cílů projektu vynikajícím způsobem. (cs)
http://linked.open...tniCyklusProjektu	ZBBBKU
http://linked.open.../cep/klicoveSlovo	muscle binding calcium chains heavy human muscle myosin phenotype proteins transplantation
is http://linked.open...vavai/riv/projekt of	Effects of long-term thyroid hormone level alterations, n-3 polyunsaturated fatty acid supplementation and statin administration in rats Maladaptive Myocardial Responses to Hypertension are Attenuated by Omega-3 Fatty Acids and Red Palm Oil Intake Electrophoretic Mobility of Cardiac Myosin Heavy Chain Isoforms Revisited: Application of MALDI TOF/TOF Analysis Glycerol-3-phosphate Dehydrogenase Expression and Oxygen Consumption in Liver Mitochondria of Female and Male Rats with Chronic Alteration of Thyroid Status Comparison of new ELISA method with established SDS-PAGE method for determination of muscle myosin heavy chain isoforms Comparison of myosin heavy chain mRNAs, protein isoforms and fiber type proportions in the rat slow and fast muscles Dietary omega-3 fatty acids attenuate myocardial arrhythmogenic factors and propensity of the heart to lethal arrhythmias in a rodent model of human essential hypertension Vývoj radiometrických metod pro stanovení enzymových aktivit jodothyronin dejodas: Vliv antidepresiva fluoxetinu na aktivity dejodas typu 1, 2 a 3 v mozku potkana Development of extremely sensitive radiometric enzyme assays Radioiodine tracers as useful tools in studies of thyrotoxic effects of exogenous bromide and perchlorate ions Radiometric quantification of thyrotoxic and goitrogenic effects of exogenous bromide and perchlorate ions Expression of the skeletal calsequestrin isoform in normal and regenerated skeletal muscles and in the hearts of rats with altered thyroid status Calsequestrin distribution, structure and function, its role in normal and pathological situations and the effect of thyroid hormones Use of Br-82 and I-131 radionuclides in studies of goitrogenic effects of exogenous bromide Xenobiotic fluoxetine interacts with the metabolism of thyroid hormones N-3 Polyunsaturated Fatty Acids Supplementation Does not Affect Changes of Lipid Metabolism Induced in Rats by Altered Thyroid Status Ascertainment of variations in the biological half-lives of bromide and sodium ions in the rat by in vivo gamma-ray measurement of 82Br and 24Na radionuclides Novel Composite Hyaluronan/Type I Collagen/Fibrin Scaffold Enhances Repair of Osteochondral Defect in Rabbit Knee Expression of nestin, desmin and vimentin in intact and regenerating muscle spindles of rat hind limb skeletal muscles Demonstration of myosim heavy chain isoforms in rat and humans:the specificity of seven available monoclonal antibodies used in immunohistochemical and immunoblotting methods Real Time RT-PCR with a Newly Designed Set of Promers Confirmed the Presence of 2b and 2x/d Myosim Heavy Chain mRNAs in the Rat Slow Soleus Muscle The role of spinal cord vanilloid (TRPV1) receptors in pain modulation The detection of the non-M2 muscarinic receptor subtype in the rat heart atria and ventricles Specific Metabolic Properties of Rat Oculorotatory Extraocular Muscles Can Be Linked to Their Low Force Requirements Parvalbumin and TRPV1 receptor expression in dorsal root ganglion neurons after acute peripheral inflammation Fiber type composition of unoperated rat soleus and extensor digitorum longus muscles after unilateral isotransplantation of a foreign muscle in long-term experiments Changes of parvalbumin expression in the spinal cord after peripheral inflammation Diabetes and thyroid hormones affect connexin-43 and PKC-ε expression in rat heart atria Thyroid hormones and cardiac arrhythmias Individual, age and sex differences in fiber type composition of slow and fast muscles of adult Lewis rats: comparison with other rat strains Development of radiometric assays for quantification of enzyme activities of the key enzymes of thyroid hormones metabolism Slow to fast muscle transformation following heterochronous isotransplantation is influenced by host thyroid hormone status
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2008/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2009/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2010/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2011/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2012/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F08%2F0256/2013/ico%3A67985823

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