About: Development of theoretical and software models of capillary electrophoresis and their application for the separation of biomolecules

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About: Development of theoretical and software models of capillary electrophoresis and their application for the separation of biomolecules Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GA203/04/0098
Description	Theoretical investigation and formulation of both the linear and nonlinear models of electromigration in Solutions of amphoteric and polyvalent electrolytes. Development of software enabling prediction of behavior of electrolyte systems for capillary electrophoresis with amphoteric and polyvalent electrolytes. The software will be user-friendly, intuitive and directed for practical applications. Application of the theoretical and software tools for the development and optimisation of the new electrolyte systems for the analysis and separation of biomolecules, namely amino acids and biologically active peptides and their derivatives and fragments. Experimental determination of mobilities and dissociation constants of biologically important compounds that will be used as input data for the software models. (en) Teoretický výzkum a formulace lineárních a nelineárních modelů elektromigrace v roztocích amfoterických a polyvalentních elektrolytů. Vývoj softwaru umožňujícího predikci chování elektrolytových systémů pro kapilární elektroforézu s amfoterními a polyvalentními elektrolyty. Software bude uživatelsky přívětivý, intuitivní a bude zaměřen na využití v praktických aplikacích. Použití teoretických a softwarových modelů pro vývoj a optimalizaci nových elektrolytových systémů pro analýzu a separaci biomolekul, především aminokyselin, biologicky aktivních peptidů a jejich derivátů a fragmentů. Experimentální stanovení mobilit a disociačních konstant biologicky významných látek, které boudou použity jako vstupní data pro počítačové modely.
Title	Development of theoretical and software models of capillary electrophoresis and their application for the separation of biomolecules (en) Vývoj teoretických a softwarových modelů kapilární elektroforézy a jejich aplikace pro separaci biomolekul
skos:notation	GA203/04/0098
http://linked.open...avai/cep/aktivita	Standard projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GA203%2F04%2F0098/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GA203%2F04%2F0098/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2007-10-16 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	2315120
http://linked.open...ai/cep/hlavniObor	CB - Analytická chemie, separace
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	Neuvedeno. (en)
http://linked.open...ep/partnetrHlavni	Přírodovědecká fakulta
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	1 (xsd:int)
http://linked.open.../pocetVysledkuRIV	31 (xsd:int)
http://linked.open...enychVysledkuVRIV	31 (xsd:int)
http://linked.open...okUkonceniPodpory	2006
http://linked.open...okZahajeniPodpory	2004
http://linked.open...iciPoslednihoRoku	2006
http://linked.open...atUdajeProjZameru	2007
http://linked.open.../vavai/cep/soutez	SGA02004GA-ST
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open.../cep/vedlejsiObor	CF - Fyzikální chemie a teoretická chemie CE - Biochemie
http://linked.open...jektu+dodavatelem	We have formulated the set of nonlinear partial differential equations describing the transport of mass and the set of nonlinear algebraic equations describing acid base equilibria in electromigration of any number of weak multivalent electrolytes (acids (en) Formulovali jsme sadu nelineárních parciálních diferenciálních rovnic popisujících transport látky a sadu nelineárních algebraických rovnic popisující acidobazické rovnováhy při elektromigraci libovolného počtu slabých vícesytných konstituentů (kyselin, (cs)
http://linked.open...tniCyklusProjektu	ZBKU
is http://linked.open...vavai/riv/projekt of	Kohlrausch regulating function and other conservation laws in electrophoresis Eigenmobilities in background electrolytes for CZE. V. Intensity (amplitudes) of system peaks Oscillating electrolytes Determination of limiting mobilities and dissociation constants of 21 amino acids by capillary zone electrophoresis at very low pH Separation and investigation of structure-mobility relationship of gonadotropin-releasing hormones by capillary zone electrophoresis in conventional and isoelectric acidic background electrolytes Analysis and separation of enkephalin and dalargin analogues and fragments by capillary zone electrophoresis Carrier ampholytes-based capillary electrophoresis as an alternative to capillary zone electrophoresis in classical background electrolytes Analysis, separation and investigation of structure-mobility relationships of biopeptides by capillary zone electrophoresis Recent advances in capillary electrophoresis of peptides and proteins Capillary zone electrophoresis in strongly acidic background electrolytes and its application to separation and characterization of peptides and pseudopeptide stereoisomers Investigation of structure-mobility relationships and estimation of secondary structure of biopeptides by capillary zone electrophoresis Separation of synthetic oligopeptides and terbutaline enantiomers by capillary zone electrophoresis with electroosmotic flow controlled by radial electric field Capillary electrophoresis assay for D-serine Physicochemical characterization of peptides and proteins by capillary electromigration methods Analyses of enkephalin and dalargin analogues and fragments by capillary zone electrophoresis PeakMaster - A freeware simulator of capillary zone electrophoresis Investigation of the effect of ionic strength of Tris-acetate background electrolyte on electrophoretic mobilities of mono-, di-, and trivalent organic anions by capillary electrophoresis Limitní pohyblivosti a disociační konstanty kationtových forem vybraných aminokyselin stanovované CZE v kyselé pH oblasti Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogues and related compounds by capillary zone electroforesis Recent developments in capillary electrophoresis and capillary electrochromatography of peptides Physicochemical characterization of biopeptides by capillary electrophoresis in background electrolytes within a broad pH range (1.4-12.0) Determination of D-serine by capillary electrophoresis Capillary electrophoresis method for the determination of D-serine and its application for monitoring of serine racemase activity Recent applications of conductivity detection in capillary and chip electrophoresis Determination of purity degree and counter-ions content in lecirelin preparations by capillary zone electrophoresis and capillary isotachophoresis Determination of pKa values of diastereomers of phosphinic pseudopeptides by CZE Control of EOF in CE by different ways of application of radial electric field Simul 5 - Free dynamic simulator of electrophoresis Conductivity detection in capillary zone electrophoresis: Inspection by PeakMaster Prediction and understanding system peaks in capillary zone electrophoresis Application of capillary and free-flow electromigration techniques in the development and production of peptide drugs in the pharmaceutical industry
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2004/ico%3A61388963 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2004/orjk%3A11310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2005/ico%3A61388963 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2005/orjk%3A11310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2006/ico%3A61388963 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2006/orjk%3A11310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2007/ico%3A61388963 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F04%2F0098/2007/orjk%3A11310

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