About: Relation among microscopic arrangement of biological tissues, function of cytoskeleton, and mechanical properties of living

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About: Relation among microscopic arrangement of biological tissues, function of cytoskeleton, and mechanical properties of living Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GA106/09/0734
Description	Vytvoření počítačového modelu vybraných živých tkání s různými modely buněčného cytoskeletu tak, aby bylo možno testovat vliv různých aspektů cytoskeletu na mechanické chování tkání. Modely identifikovat a testovat mechanickými měřeními tkání doplněnými stereologickým a mikroskopickým vyhodnocením. The proposed project aims to model mechanical properties of living tissues by using the scale approaches (microcontinuum) in order to include parameters of cellular cytoskeleton into the resulting continuum models. To reveal an influence of various features of the cytoskeleton on mechanical behavior of tissues, we will apply several approaches modelling the cytoskeleton (as a tensegrity structure, semiflexible polymer network, and ontinuum structure with the rheology of soft glassy materials). Resulting continuum models of tissues will be tested by means of measurement of mechanical properties of macroscopic tissue samples which microscopic structure will be modified by chemical interventions (leading for instance to %22switching off%22 of various components of the cytoskeleton). Microscopic structure of tissue will be investigated and evaluated by modernstereological methods as well as the confocal microscopy. Resulting continuum models will be used in modeling of smooth muscle within wall of veins and biomechanics of corio-epidermal suspension of the distal phalanx in horse. (en)
Title	Relation among microscopic arrangement of biological tissues, function of cytoskeleton, and mechanical properties of living (en) Vliv mikroskopického uspořádání tkání a funkce buněčného cytoskeletu na mechanické vlastnosti živých tkání
skos:notation	GA106/09/0734
http://linked.open...avai/cep/aktivita	Standard projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GA106%2F09%2F0734/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GA106%2F09%2F0734/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-03-02 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	91487916
http://linked.open...ai/cep/hlavniObor	JJ - Ostatní materiály
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	biomechanika tkání, cytoskeleton, mechanické vlastnosti živých tkání (en)
http://linked.open...ep/partnetrHlavni	Fakulta aplikovaných věd
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	1 (xsd:int)
http://linked.open.../pocetVysledkuRIV	20 (xsd:int)
http://linked.open...enychVysledkuVRIV	20 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-04-16 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/106%2F09%2F0734
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open.../vavai/cep/soutez	SGA02009GA-ST
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-12-31 (xsd:date)
http://linked.open...ep/zahajeniReseni	2009-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en) Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	cytoskeleton biomechanika tkání
is http://linked.open...vavai/riv/projekt of	Fyzika a živé struktury. Odkud povstávají mechanické vlastnosti živé hmoty A preliminary study into the correlation of stiffness of the laminar junction of the equine hoof with the length density of its secondary lamellae Generalized %22grid%22 continuum description as a tool for proposing multi-scale material models Constitutive modelling of an arterial wall supported by microscopic measurements Aorta remodelling associated with calcitonin gene related peptide concentration in rats with arterial hypertension A model of Engineering Materials Inspired by Biological Tissues Microstructure-dependent nonlinear viscoelasticity due to extracellular flow within cellular structures Prestress in Work - from Engineering Constructions to Living Cells Smooth Muscle as an Inspiration for Designing Engineering Materials Fyzika a živé struktury Surface density of dermo-epidermal lamellae and mechanical testing of suspensory apparatus of equine hoof Modelling of the mechanical behaviour of porcine carotid artery undergoing inflation-deflation test Grid continuum description: A novel approach in two-scale hyperelasticity Constitutive modelling of an arterial wall supported by microscopic measurements The contribution of vascular smooth muscle, elastin and collagen on the passive mechanics of porcine carotid arteries Finite element model of the equine hoof Modelling of the mechanical behaviour of porcine carotid artery undergoing perfusion test Microcracks and mechanical behaviour of corio-epidermal junction of equine hoof Mechanical Properties of Living Cells and Tissues Related to Thermodynamics, Experiments and Quantitative Morphology - A Review Vasa vasorum quantification in human varicose great and small saphenous veins
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2009/orjk%3A11320 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2009/orjk%3A23520 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2010/orjk%3A11320 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2010/orjk%3A23520 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2011/orjk%3A11320 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2011/orjk%3A23520 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2012/orjk%3A11320 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA106%2F09%2F0734/2012/orjk%3A23520

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