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Description
  • *Research in the area of intermediates for MRI with the target to obtain data for technology of production for these intermediates, piloting and preparation of products for quality testing (en)
  • *Výzkum v oblasti intermediátů pro magnetickou resonanci (MRI - Magnetic Resonance Imagination) se zaměřením na získání podkladů pro technologii výroby těchto intermediátů, čtvrtprovozní ověření technologie a příprava produktů pro testování kvality.
Title
  • *Intermediates for MRI contrast media (en)
  • *Intermediáty pro MRI kontrastní látky.
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  • 2A-1TP1/040
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  • Kontrast media; magnetic resonance imagination; key intermediates; cyclene; Klobenprop (en)
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  • Preparation of 1,4,7,10-tetraazacyclododecane (cyclen) and potassium salts of 3-benzyloxy-2-chlorpropanoic acid (klobenprop), which are the intermediates for preparation of MRI contrast agents. The workflow for preparation in a pilot scale was developed. (en)
  • Příprava 1,4,7,10-tetraazacyklododecanu (cyklen) a draselné soli 3-benzyloxy-2-chlorpropanové kyseliny (klobenprop), intermediátů pro MRI kontrastní látky. Proveden laboratorní výzkum syntézy a prac. postupy na přípravu v poloprovozním měřítku. (cs)
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  • cyclene
  • key intermediates
  • magnetic resonance imagination
  • Kontrast media
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