About: Oral health state in children included in Brno ELSPAC study     Goto   Sponge   NotDistinct   Permalink

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  • The project studies prevalence of the dental caries and gingivitis/periodontitis in 800-1000 children involed in ELSPAC study with the aim to find out the level of oral health and to determine strategy of prevention of these multifactorial diseses. Presence of oral pathogens, which can play a role in aethiology of severe systemic diseases, will be studied microbiologically in 150 children with healthy gingiva and in 150 children with gingivitis. The study will assess the contribution of polymorphism in genes which influence inflammation and tissue remodelling responses in aethiopathogenesis of chronic gingivitis/periodontitis. Relation of genotypes to disease progression will also be evaluated. (en)
  • Práce studuje prevalenci zubního kazu, zánětu dásní a parodontu u 800-1000 dětí ve věku 13-15 let zařazených dp prograu ELSPAC s cílem zjistit úroveň orálního zdraví a stanovit strategii prevence těchto multifaktoriálních chorob. V mikrobiologické části projektu bude u 150 dětí s gingivitis a u 150 dětí se zdravou dásní stanovena přítomnost orálních patogenů, které se mohou uplatnit v etiopatogenesi závažných systémových chorob. Budou využity údaje z ELSPAC databáze. Cílem projektu je zhodnotit možný vliv polymorfismů v genech ovlivňujících zánět a tkáňovou remodelaci v etiopatogenezi gingivitis/parodontitis. Použité metody umožní posoudit i vztah genotypu k progresi choroby. (cs)
Title
  • Oral health state in children included in Brno ELSPAC study (en)
  • Stav orálního zdraví u dětí sledovaných v programu ELSPAC Brno (cs)
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  • caries; gingivitis; periodontitis; microbiology; genetics; DMFT-index; Silness-Löe-index; ELSPAC (en)
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