About: The molecules regulating osteoclast differentiation and their contribudion in rheumatoid arthritis bone resorption

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About: The molecules regulating osteoclast differentiation and their contribudion in rheumatoid arthritis bone resorption Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	Bude provedeno srovnání systémové a lokální exprese moleku RANKL na T lymfocytech a hodnocení exprese RANK a RANKL na různých buněčných typech synoviální tkáně metodou imunohistochemie a průtokové cytometrie u pacientů s aktivní revmatoidní artritidou a artrózou. AnII. Bude provedeno porovnání hladin osteoprotegerinu v séru a synoviálním výpotku stanovených metodou ELISA u obou skupin nemocných . Nálezy budou vztaženy k aktivitě artritidy a parametrům kostní přeměny. (cs) The relation of local and systemic expression of RANKL on T lymphocytes and the RANK and RANKL ewpression on synovial tissue cells will be studied by immunohistochemisty and flow cytometry in patients with active rheumatoid arthritis and osteoarthrits. The levels of OPG evaluated by ELISA method in serum and synovial fluid will be compared in both group of patiens and related to disease activity and bone turnover markers. The between group comparison will be made. (en)
Title	The molecules regulating osteoclast differentiation and their contribudion in rheumatoid arthritis bone resorption (en) Molekuly regulující diferenciaci osteoklastů a jejich účast při resorpci kosti u revmatoidní artritidy (cs)
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http://linked.open...vai/klicova-slova	rheumatoid;arthritis;osteoprotegerin;RANK;RANKL;osteoclastogesis;osteoarthritis;osteoporosis (en)
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