About: Detection and characterisation of HIV-1 mutants resistant to specific therapy with protease inhibitors: evolution of the resistant species and their interactions with other viral proteins     Goto   Sponge   NotDistinct   Permalink

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  • Studium resistentních kmenů HIV v pacientech léčených inhibitory proteasy. Sekvenování, klonování a charakterisace rekombinantních mutantních proteas. Návrh specifických inhibitorů. Evoluce proteasy a dalších virových genů u HIV positivních pacientů. (cs)
  • Resistant HIV strains in patients treated by protease inhibitors. Sequencing, cloning and analysis of recombinant mutant proteases. Design of a broad specificity inhibitor. Co-evolution of protease and pther viral genes in HIV under selection pressure. (en)
Title
  • Detection and characterisation of HIV-1 mutants resistant to specific therapy with protease inhibitors: evolution of the resistant species and their interactions with other viral proteins (en)
  • Detekce a charakterisace mutantů viru HIV-1 resistentních vůči inhibitorům virové proteasy: evoluce resistentních proteas a jejich interakce s dalšími virovými proteiny (cs)
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  • HIV;AIDS;protease;virus resistance;DNA sequencing;vif;nef (en)
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