About: The proteome center for the study of intracellular parasitism of microbes

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description	Vytvořit centrum proteomových studií schopné analyzovat složité procesy vedoucí k závažným dosud terapeuticky nezvládnutým onemocněním člověka. Připravit školící mezioborové pracoviště pro komplexní, moderní, laboratorní technologie.Proteomová analýza intracelulárních bakteriálních patogenů s cílem nalézt takové znaky mikrobů, které jsou využitelné k jejich diagnostice, mají vztah k jejich invazivitě a virulenci a dále identifikovat jejich imunoreaktivní složky.Studium molekulárních interakcí v průběhu časné fáze infekce eukaryotických buněk a organizmů pro pochopení podstaty intracelulárního parazitizmu a nalezení profylaktické a terapeutické strategie. (cs) To establish the center for proteome studies capable to analyze complex processes leading to serious up to now therapeutically uncontrolled human diseases. To prepare educational interdisciplinary facility for complex modern laboratory technologies.The proteome study of intracellular pathogens with the aim to find microbial markers suitable for diagnostics, markers associated with microbial invasiveness and virulance and, furthermore, to identify microbial immunoreactive components.The study of molecular interactions occurring in the early phase of infection of eucaryotic cells and whole organisms in order to get better understanding of the basis of intracellular parasitism and to find new prophylactic and therapeutic strategies. (en)
Title	Proteomové centrum pro studium intracelulárního parazitizmu bakterií (cs) The proteome center for the study of intracellular parasitism of microbes (en)
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http://linked.open...vai/klicova-slova	intracellular parasitism; proteome; intracellular bacteria; virulence factors; cytokines; CD markers; cellular organelles; gene expression (en)
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