About: The role of repetitive DNA in plant genome architecture and function     Goto   Sponge   NotDistinct   Permalink

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  • Cílem projektu je aplikace nejmodernějších sekvenačních, bioinformatických a molekulárně-cytogenetických metod na výzkum repetitivní DNA v genomech vyšších rostlin. Projekt je zaměřen především na zjištění složení repetitivních sekvencí v druzích lišících se velikostí a dalšími vlastnostmi svých genomů, na objasnění strukturní a funkční úlohy repetitivní DNA v centromerách a dalších specifických oblastech chromozómů a dále na výzkum molekulárních mechanizmů způsobujících hromadění nebo eliminaci repetic v genomech rostlin. (cs)
  • Repetitive DNA, composed of diverse families of mobile elements and tandem repeats, makes up significant portions of most higher plant genomes. Despite the growing acknowledgment of the repetitive DNA as one of the major forces shaping plant genomes, there is relatively little known about molecular and evolutionary mechanisms of repetitive DNA turnover in plant genomes, and about specific functions it plays in genome architecture. In this project, we propose to employ a combination of advanced sequencing, bioinformatic and cytogenetic approaches to elucidate these problems by investigating repetitive DNA on various levels, including whole genomes, defined genome compartments, and specific families of repetitive DNA. (en)
Title
  • The role of repetitive DNA in plant genome architecture and function (en)
  • Repetitivní DNA a její význam pro strukturu a funkci rostlinného genomu (cs)
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  • plant genome; repetitive DNA; evolution; mobile elements; satellite repeats; genome evolution; sequencing (en)
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