About: Microtubules in activated mast cells - targets for innovative therapies

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
Description	Cílem projektu je 1. Určit složení a funkci komplexů obsahujících tubulin a signální molelkuly v aktivovaných žírných buňkách. 2. Charakterizovat interakce gama-tubulinu s fosfoinositid-3-kinázou a protein tyrosin kinázami Src rodiny. 3. Určit nové modulátorz (inhibitory/aktivátory) tvorby mikrotubulů při degranulaci a chemotaxi u myších a lidských žírných buněk. (cs) The aims othis project are: 1. To identify composition and function of complexes containing tubulins and signalling molecules in activated mast cells. 2. To characterize gamma-tubulin interactions with phosphoinositide-3-kinase and Src family kinases. 3. To find inhibitors and enhancers of microtubule formation during degranulation and chemotaxis in mast cells of mouse and human origin. (en)
Title	Mikrotubuly v aktivovaných žírných buňkách - cíle pro inovativní terapie (cs) Microtubules in activated mast cells - targets for innovative therapies (en)
http://linked.open...vai/cislo-smlouvy	http://linked.opendata.cz/resource/domain/vavai/cep/smlouva/MSMT-9339/2013-311
http://linked.open...avai/druh-souteze	http://linked.opendata.cz/resource/domain/vavai/cep/druh-souteze/VS
http://linked.open...domain/vavai/faze	http://linked.opendata.cz/resource/domain/vavai/cep/faze/54636618
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http://linked.open...n/vavai/kategorie	http://linked.opendata.cz/resource/domain/vavai/cep/kategorie/1
http://linked.open...vai/klicova-slova	microtubule dynamics in mast cells; microtubule dynamics in mast cells (en)
http://linked.open...avai/konec-reseni	2014-12-31 (xsd:date)
http://linked.open...nujicich-prijemcu	0 (xsd:integer)
http://linked.open...avai/poskytovatel	http://linked.opendata.cz/resource/domain/vavai/cep/poskytovatel/MSM
http://linked.open...avai/start-reseni	2013-03-21 (xsd:date)
http://linked.open...ai/statni-podpora	942 (xsd:integer)
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is http://linked.open...ain/vavai/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2013/LD13015/ico-68378050 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/2014/LD13015/ico-68378050

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