About: *The development of a plasma free metanephrine analysis kit     Goto   Sponge   NotDistinct   Permalink

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  • *When diagnosing pheochromocytoma, the most commonly ušed laboratory analysis method for catecholamines and their metabolites, especially metanephrine and normetanephrine, in urine and plasma, is HPLC. This method is usu-ally developed and validated by individual laboratories as there is no affordable plasma free metanephrine analysis kit manufactured in the EU. This project is a concept fordevelopment of a new plasma free metanephrine HPLC analysis kit. Certified method of analysis will respect interfering effects of pharmaceuticals and their metabolites in plasma and variability of matrix effects. (en)
  • *Při diagnostikování feochromocytomu se používá laboratorní metoda stanovení katecholaminů a jejich metabolitů, zejména metanefrinu a normetanefrinu v moči a v plazmě, nejběžněji metoda HPLC, kterou si jednotlivé laboratoře sami vyvíjejí a validují, jelikož v EU cenově dostupný kit pro stanovení plazmatických metanefrinu nikdo nevyrábí. Projekt je návrhem vývoje nového kitu pro HPLC stanovení plazmatických metanefrinů. Certifikovaná metoda stanovení bude respektovat interferující efekty léčiv a jejich metabolitů v plazmě a variabilitu matričních efektů. (cs)
Title
  • *Vývoj kitu pro stanovení plazmatických metanefrinů (cs)
  • *The development of a plasma free metanephrine analysis kit (en)
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  • kit; metanephrines; plasma; plasma metanephrines; katecholamines (en)
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