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  • *Vývoj syntézy tří vybraných aktivních farmaceutických substancí z terapeutických skupin antidepresiv, antiglaukomatik a antimigrenik do stadia scale-up ověřovacích šarží. Výběr substancí směřuje k obohacení portfolia léčiv na českém trhu o značkové ekvivalenty terapeuticky významných léčiv. V přípravě opticky aktivních substancí budou ověřeny možnosti využití asymetricky katalyzovaných reakcí. (cs)
  • *The development of synthesis of three active pharmaceutical substances (APIs) belonging to the pharmaceuticals for the treatment of depression, glaucoma and migraine to the pilot-plant technology. The choice of substances aims at enriching of the pharmaceutical portfolio of Czech market on generic modificationd of therapeutically important drugs. The possibility of the utilization of asymetric catalyzed reactions in the preparation of enantiomeric active substances will be studies. (en)
Title
  • *Chirální syntézy v přípravě aktivních farmaceutických substancí. (cs)
  • *Chiral syntheses in the preparation of active pharmaceutical substances (APIs). (en)
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  • active pharmaceutical ingredients; development of synthesis; optical isomers; asymetric catalyzed reactions (en)
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