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Description
| - In the present study we quantified cell volume changes in astrocytes lacking α-syntrophin thanks to the successful generation of GFAP/EGFP/α-Syn-/- mice, which enabled us to visualize astrocytes based on EGFP expression. We demonstrated that α-syntrophin knockout results in smaller astrocytic swelling when induced by severe hypoosmotic stress, OGD or high extracellular K+, and it also affects astrocyte volume changes during the washout period following mild hypo- and hyperosmotic stress, and 10 mMK+.
- In the present study we quantified cell volume changes in astrocytes lacking α-syntrophin thanks to the successful generation of GFAP/EGFP/α-Syn-/- mice, which enabled us to visualize astrocytes based on EGFP expression. We demonstrated that α-syntrophin knockout results in smaller astrocytic swelling when induced by severe hypoosmotic stress, OGD or high extracellular K+, and it also affects astrocyte volume changes during the washout period following mild hypo- and hyperosmotic stress, and 10 mMK+. (en)
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Title
| - Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
- Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice (en)
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skos:prefLabel
| - Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
- Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice (en)
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skos:notation
| - RIV/86652036:_____/14:00436669!RIV15-GA0-86652036
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(ED1.1.00/02.0109), P(GA13-02154S), P(GBP304/12/G069)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/86652036:_____/14:00436669
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - astrocyte volume regulation; aquaporines; extracellular space (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Benešová, Jana
- Kubista, Mikael
- Vargová, L.
- Anděrová, Miroslava
- Džamba, Dávid
- Honsa, Pavel
- Butenko, Olena
- Valihrach, Lukáš
- Mikešová, Michaela
- Cicanič, M.
- Dmytrenko, L.
- Kriška, Ján
- Novosadová, Vendula
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1371/journal.pone.0113444
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