About: Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor

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About: Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We present a novel surface plasmon resonance (SPR) biosensor for detection of human interferon gamma (hIFNy), an important diagnostic marker for several infectious diseases. The biosensor employs engineered proteins derived from albumin binding domain (ABD) and selected with ribosome display to provide high affinity towards hIFNy. We demonstrate that the biosensor provides rapid, sensitive, and cost-effective platform for the detection of hIFNγ and allows its detection at nanomolar levels both in buffer and diluted human plasma We present a novel surface plasmon resonance (SPR) biosensor for detection of human interferon gamma (hIFNy), an important diagnostic marker for several infectious diseases. The biosensor employs engineered proteins derived from albumin binding domain (ABD) and selected with ribosome display to provide high affinity towards hIFNy. We demonstrate that the biosensor provides rapid, sensitive, and cost-effective platform for the detection of hIFNγ and allows its detection at nanomolar levels both in buffer and diluted human plasma (en)
Title	Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor (en)
skos:prefLabel	Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor (en)
skos:notation	RIV/86652036:_____/11:00437424!RIV15-AV0-86652036
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KAN200520702), P(KAN200670701), P(OC09058), Z(AV0Z20670512), Z(AV0Z50200510), Z(AV0Z50520701)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Mikulecký, Pavel Kuchař, Milan Šebo, Peter Malý, Petr
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biotechnologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	228827
http://linked.open...ai/riv/idVysledku	RIV/86652036:_____/11:00437424
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Surface plasmon resonance; Biosensor; Interferon gamma (en)
http://linked.open.../riv/klicoveSlovo	Surface plasmon resonance Biosensor Interferon gamma
http://linked.open...ontrolniKodProRIV	[D6FF8C80A25F]
http://linked.open...v/mistoKonaniAkce	Athens
http://linked.open...i/riv/mistoVydani	Amsterdam
http://linked.open...i/riv/nazevZdroje	Procedia Engineering
http://linked.open...in/vavai/riv/obor	EI
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Plasmonic nanostructures and functionalizations for optical affinity biosensors Surface plasmon resonance biosensors and protein arrays for medical diagnostics Nanoimmunosensors for detection of cytokines
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Homola, Jiří Šebo, Peter Malý, Petr Šípová, Hana Ahmad, Jawid Kuchař, Milan Mikulecký, Pavel Ševců, Veronika
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open...ain/vavai/riv/wos	000300512400228
http://linked.open.../riv/zahajeniAkce	2011-09-04 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Materiály, struktury, systémy a signály v elektronice, optoelektronice a fotonice Microorganisms in Research and Biotechnology Establishing of the Biotechnology Institute ASCR
issn	1877-7058
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.proeng.2011.12.231
http://purl.org/ne...btex#hasPublisher	Elsevier
https://schema.org/isbn	978-1-62748-581-4

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