About: Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency     Goto   Sponge   NotDistinct   Permalink

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  • New CD21-CD38-CD27-CD24+IgM+ and CD21-CD38- CD27-CD24-IgM+ subpopulations of B lymphocytes were shown using molecular analysis to display the signs of antigen-driven selection, affinity maturation and isotype switching in both patients with immunodeficiences and controls. These populations can be easily identified using so-called binning algorithm allowing generation of clusters of patients and B lymphocyte subsets. The validity of this method was verified using classical flow cytometry gating and correlation between flow cytometry data and clinical parameters
  • New CD21-CD38-CD27-CD24+IgM+ and CD21-CD38- CD27-CD24-IgM+ subpopulations of B lymphocytes were shown using molecular analysis to display the signs of antigen-driven selection, affinity maturation and isotype switching in both patients with immunodeficiences and controls. These populations can be easily identified using so-called binning algorithm allowing generation of clusters of patients and B lymphocyte subsets. The validity of this method was verified using classical flow cytometry gating and correlation between flow cytometry data and clinical parameters (en)
Title
  • Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency
  • Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency (en)
skos:prefLabel
  • Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency
  • Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency (en)
skos:notation
  • RIV/86652036:_____/09:00335460!RIV10-AV0-86652036
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR9198), Z(AV0Z50520701)
http://linked.open...iv/cisloPeriodika
  • 11
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 336844
http://linked.open...ai/riv/idVysledku
  • RIV/86652036:_____/09:00335460
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • binning; B lymphocyte profiling; common variable immunodeficiency (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [B481FA9688B5]
http://linked.open...i/riv/nazevZdroje
  • Cytometry. Part A
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 75
http://linked.open...iv/tvurceVysledku
  • Hrušák, O.
  • Růžičková, Šárka
  • Kalina, T.
  • Vlková, M.
  • Šedivá, A.
  • Janda, A.
  • Litzman, J.
  • Stuchlý, J.
http://linked.open...ain/vavai/riv/wos
  • 000271498500003
http://linked.open...n/vavai/riv/zamer
issn
  • 1552-4922
number of pages
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