About: Seminal plasma and sperm surface proteins and their role in reproduction

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Boar seminal plasma (SP) protein AQN 1 spermadhesin binds to the sperm plasma membrane that overlies the outer acrosomal membrane and has been implicated in sperm binding to the zona pellucida (ZP) as well as in sperm interactions with the epithelium of the oviductal sperm reservoir. Human SP was found to be very low in AQN 1 spermadhesin–like proteins. Ubiquitin C-terminal hydrolases (UCHs) are responsible for the removal of polyubiquitin chains during protein priming for proteasomal proteolysis. Modulation of UCH activity could facilitate the management of polyspermy during IVF and provide insight into male infertility. Boar sperm UCHL3 was localized to the acrosomal surface and coimmunoprecipitated with boar AQN 1 spermadhesin. Boar seminal plasma (SP) protein AQN 1 spermadhesin binds to the sperm plasma membrane that overlies the outer acrosomal membrane and has been implicated in sperm binding to the zona pellucida (ZP) as well as in sperm interactions with the epithelium of the oviductal sperm reservoir. Human SP was found to be very low in AQN 1 spermadhesin–like proteins. Ubiquitin C-terminal hydrolases (UCHs) are responsible for the removal of polyubiquitin chains during protein priming for proteasomal proteolysis. Modulation of UCH activity could facilitate the management of polyspermy during IVF and provide insight into male infertility. Boar sperm UCHL3 was localized to the acrosomal surface and coimmunoprecipitated with boar AQN 1 spermadhesin. (en)
Title	Seminal plasma and sperm surface proteins and their role in reproduction Seminal plasma and sperm surface proteins and their role in reproduction (en)
skos:prefLabel	Seminal plasma and sperm surface proteins and their role in reproduction Seminal plasma and sperm surface proteins and their role in reproduction (en)
skos:notation	RIV/86652036:_____/09:00326916!RIV10-MSM-86652036
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M06011), P(GA303/09/1285), P(GD523/08/H064), Z(AV0Z50520701)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Jonáková, Věra Pěknicová, Jana Cozlová, Nina Maňásková-Postlerová, Pavla
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biotechnologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	340758
http://linked.open...ai/riv/idVysledku	RIV/86652036:_____/09:00326916
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	spermadhesin; human seminal plasma; ubiquitin C-terminal hydrolase (en)
http://linked.open.../riv/klicoveSlovo	human seminal plasma spermadhesin ubiquitin C-terminal hydrolase
http://linked.open...ontrolniKodProRIV	[75C617A003E2]
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	The Centre of Molecular Methods for Monitoring the Diffuse Pollution of the Environment. Study of the sperm membrane proteins with zona pellucida binding activity Biotechnologies of mammalian gametes
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Davidová, Nina Jonáková, Věra Pěknicová, Jana Tichá, M. Šutovský, P. Postlerová, Pavla
http://linked.open...n/vavai/riv/zamer	Establishing of the Biotechnology Institute ASCR

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