About: The Lack of Correlation between the Increased Frequency of Allele IL-1RN*2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation

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About: The Lack of Correlation between the Increased Frequency of Allele IL-1RN*2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Fifty patients with primary knee osteoarthritis (OA) and 170 healthy controls were tested in order to determine whether the IL-1RN2 allele could be a factor predisposing to development of knee OA in general and/or whether it could correlate with the markers of cartilage destruction, additionally affecting the course and severity of the disease. The results suggest that the IL-1RN2 allele might represent a factor of susceptibility to OA generally; however, no correlation between this allele and the markers of cartilage degradation was found. Fifty patients with primary knee osteoarthritis (OA) and 170 healthy controls were tested in order to determine whether the IL-1RN2 allele could be a factor predisposing to development of knee OA in general and/or whether it could correlate with the markers of cartilage destruction, additionally affecting the course and severity of the disease. The results suggest that the IL-1RN2 allele might represent a factor of susceptibility to OA generally; however, no correlation between this allele and the markers of cartilage degradation was found. (en)
Title	The Lack of Correlation between the Increased Frequency of Allele IL-1RN2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation The Lack of Correlation between the Increased Frequency of Allele IL-1RN2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation (en)
skos:prefLabel	The Lack of Correlation between the Increased Frequency of Allele IL-1RN2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation The Lack of Correlation between the Increased Frequency of Allele IL-1RN2 of Interleukin-1 Receptor Antagonist Gene in Czech Patients with Knee Osteoarthritis and the Markers of Cartilage Degradation (en)
skos:notation	RIV/86652036:_____/08:00312726!RIV10-AV0-86652036
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR8447), Z(AV0Z50520701)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Růžičková, Šárka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biotechnologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	376148
http://linked.open...ai/riv/idVysledku	RIV/86652036:_____/08:00312726
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	knee osteoarthritis; IL-1RN gene; VNTR polymorphism (en)
http://linked.open.../riv/klicoveSlovo	VNTR polymorphism IL-1RN gene knee osteoarthritis
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[4B544A4D1C0D]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Erosive osteoarthrosis - the scope and progression of joint affection related to a low activity systemic inflammation, evaluated using biochemical and scintigraphic methods, and to genetic predisposition.
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Šenolt, L. Růžičková, Šárka Vencovský, J. Gatterová, J. Pavelka, K.
http://linked.open...ain/vavai/riv/wos	000260284900002
http://linked.open...n/vavai/riv/zamer	Establishing of the Biotechnology Institute ASCR
issn	0015-5500
number of pages	6 (xsd:int)

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