About: Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas

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About: Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	For the first time, we have evaluated both base and nucleotide excision repair capacities in human colon biopsies to study their participation in colorectal tumorigenesis. Our complex analysis showed that tumor cells are not deficient in studied pathways, but rather follow patterns characteristic for each individual and are comparable with adjacent tissue. This study further shows the feasibility of DRC evaluation in human solid tissues, representing a complex marker of multigene DNA repair processes. For the first time, we have evaluated both base and nucleotide excision repair capacities in human colon biopsies to study their participation in colorectal tumorigenesis. Our complex analysis showed that tumor cells are not deficient in studied pathways, but rather follow patterns characteristic for each individual and are comparable with adjacent tissue. This study further shows the feasibility of DRC evaluation in human solid tissues, representing a complex marker of multigene DNA repair processes. (en)
Title	Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas (en)
skos:prefLabel	Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas (en)
skos:notation	RIV/75010330:_____/12:00009838!RIV13-GA0-75010330
http://linked.open...avai/riv/aktivita	I N P Z
http://linked.open...avai/riv/aktivity	I, N, P(GAP304/10/1286), P(GAP304/12/1585), P(NT12025), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	21
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Vodičková, Ludmila Souček, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní zdravotní ústav, příspěvková organizace
http://linked.open...dnocenehoVysledku	137378
http://linked.open...ai/riv/idVysledku	RIV/75010330:_____/12:00009838
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colorectal cancer; DNA repair (en)
http://linked.open.../riv/klicoveSlovo	colorectal cancer DNA repair
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E7B66CE907F5]
http://linked.open...i/riv/nazevZdroje	Clinical cancer research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	15 (xsd:int)
http://linked.open...vavai/riv/projekt	DNA repair and sporadic colorectal cancer. Molecular DNA repair characteristics in CRC tumor tissue Molecular-biological and histopathological characteristics of tumor infiltrating lymphocytes as instrument of prediction of risk of early colorectal cancer recurrence
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Vodičková, Ludmila Švec, J. Souček, Pavel Procházka, P. Kumar, R. Levý, M. Naccarati, A. Vodička, P. Lipská, L. Liška, V. Slýšková, J. Collins, A. R. Holubec, L. Korenková, V. Schneiderová, M.
http://linked.open...ain/vavai/riv/wos	000312020400008
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	1078-0432
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1158/1078-0432.CCR-12-1380

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