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rdf:type
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Description
| - Primary rat hepatocytes were used to test acute toxicities of 16 neutral aliphatic alcohols, ketones and esters. Their effects on cell viability and metabolic function (ureogenesis, i.e. biotransformation of ornithine to urea) were measured and expressed as EC50 values. Log EC50 values from both tests correlated with the log partition coefficients for the chemicals between n-octanol and water and log P-ow-based QSAR models were derived.
- Primary rat hepatocytes were used to test acute toxicities of 16 neutral aliphatic alcohols, ketones and esters. Their effects on cell viability and metabolic function (ureogenesis, i.e. biotransformation of ornithine to urea) were measured and expressed as EC50 values. Log EC50 values from both tests correlated with the log partition coefficients for the chemicals between n-octanol and water and log P-ow-based QSAR models were derived. (en)
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Title
| - Primary rat hepatocytes in chemical testing and QSAR predictive applicability
- Primary rat hepatocytes in chemical testing and QSAR predictive applicability (en)
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skos:prefLabel
| - Primary rat hepatocytes in chemical testing and QSAR predictive applicability
- Primary rat hepatocytes in chemical testing and QSAR predictive applicability (en)
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skos:notation
| - RIV/75010330:_____/10:00008831!RIV11-GA0-75010330
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA203/06/1265), P(GA305/03/1169)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/75010330:_____/10:00008831
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Pokorná, Adéla
- Hanzlíková, Iveta
- Tichý, Miloň
- Nerudová, Jana
- Tumová, Jana
- Uzlová, Rút
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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