About: Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene

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About: Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Both N7 guanine and N3 adenine DNA adducts derived from styrene are rapidly depurinated and eliminated in urine. Proportion of urinary N3 adenines was much higher than those expected from in vitro studies. Both N7 guanines and N3 adenines are promising biomarkers of an effective dose of styrene detactable, however, only a short-time exposure follouwing. Both N7 guanine and N3 adenine DNA adducts derived from styrene are rapidly depurinated and eliminated in urine. Proportion of urinary N3 adenines was much higher than those expected from in vitro studies. Both N7 guanines and N3 adenines are promising biomarkers of an effective dose of styrene detactable, however, only a short-time exposure follouwing. (en)
Title	Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene (en)
skos:prefLabel	Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene (en)
skos:notation	RIV/75010330:_____/09:00008406!RIV10-GA0-75010330
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA203/06/0888)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Vodičková, Ludmila Frantík, Emil Neufussová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní zdravotní ústav, příspěvková organizace
http://linked.open...dnocenehoVysledku	314119
http://linked.open...ai/riv/idVysledku	RIV/75010330:_____/09:00008406
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	styrene; biomarkers (en)
http://linked.open.../riv/klicoveSlovo	biomarkers styrene
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[EA766067B2B2]
http://linked.open...i/riv/nazevZdroje	Toxicology letters
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	N7 Substituted guanines for early diagnostics of DNA damage; development of synthetic and analytical methods
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	184
http://linked.open...iv/tvurceVysledku	Mikeš, P. Vodičková, Ludmila Frantík, Emil Kořínek, M. Krouželka, J. Linhart, I. Neufussová, Lenka
http://linked.open...ain/vavai/riv/wos	000262544400006
issn	0378-4274
number of pages	5 (xsd:int)

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