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| rdf:type
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| Description
| - Výzkum byl realizován v rámci studie CESAR ke zjištění souboru imunologických biomarkerů dětí ze 6 středoevropských zemí. Krev byla odebrána 366 školním dětem ve věku 9-11 let v roce 1996. Vztah PM10 a PM2.5 a log-transformovanou koncentrací každého biomarkeru byl analyzován lineární regresí ve dvoustupňovém modelu. Roční průměrné koncentrace se pohybovaly v rozmezí 41-96 µg/m3 u PM10 v 17 studijních oblastech, 29-67 µg/m3 u PM2.5 a 12-38 µg/m3 u PM10-2.5 (částice). Počet B, CD4 + , CD8 + , a NK lymfocytů se zvyšoval s rostoucími koncentracemi PM po adjustaci na věk, pohlaví, kouření rodičů, analyzující laboratoř a předchozí respirační onemocnění. Rozdíly v počtu lymfocytů byly větší a statisticky významné u expozice PM2.5. Celkové IgG se zvyšovalo s koncentracemi PM, statisticky významně u PM2.5. Efekt částic na počet lymfocytů byl malý v porovnání s PM2.5. (cs)
- A survey was conducted within the framework of the CESAR study to measure a panel of immune biomarkers in children from 6 CEE countries. Blood was collected from 366 school children aged 9 to 11 yr in 1996. Associations between PM10 and PM2.5 and each log-transformed biomarker concentration were studied by linear regression, in a two-stage model. The yearly average concentrations varied from 41 to 96 µg/m3 for PM10 across the 17 study areas, from 29 to 67 µg/m3 for PM2.5, and from 12 to 38 µg/m3 for PM10-2.5 (coarse). Number of B, CD4 + , CD8 + , and NK lymphocytes increased with increasing concentration of PM, having adjusted for age, gender, parental smoking, laboratory of analysis, and recent respiratory illness. Differences in lymphocyte number were larger and statistically significant for exposure to PM2.5. Total IgG was increased with increasing concentration of PM, significantly in the case of PM2.5. The effect of coarse PM on lymphocyte numbers appears small in comparison to PM2.5.
- A survey was conducted within the framework of the CESAR study to measure a panel of immune biomarkers in children from 6 CEE countries. Blood was collected from 366 school children aged 9 to 11 yr in 1996. Associations between PM10 and PM2.5 and each log-transformed biomarker concentration were studied by linear regression, in a two-stage model. The yearly average concentrations varied from 41 to 96 µg/m3 for PM10 across the 17 study areas, from 29 to 67 µg/m3 for PM2.5, and from 12 to 38 µg/m3 for PM10-2.5 (coarse). Number of B, CD4 + , CD8 + , and NK lymphocytes increased with increasing concentration of PM, having adjusted for age, gender, parental smoking, laboratory of analysis, and recent respiratory illness. Differences in lymphocyte number were larger and statistically significant for exposure to PM2.5. Total IgG was increased with increasing concentration of PM, significantly in the case of PM2.5. The effect of coarse PM on lymphocyte numbers appears small in comparison to PM2.5. (en)
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| Title
| - Imunologické biomarkery ve vztahu k expozici prašným částicím: průřezová studie v 17 městech střední Evropy (cs)
- Immune biomarkers in relation to exposure to particulate matter : a cross-sectional survey in 17 cities of Central Europe
- Immune biomarkers in relation to exposure to particulate matter : a cross-sectional survey in 17 cities of Central Europe (en)
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| skos:prefLabel
| - Imunologické biomarkery ve vztahu k expozici prašným částicím: průřezová studie v 17 městech střední Evropy (cs)
- Immune biomarkers in relation to exposure to particulate matter : a cross-sectional survey in 17 cities of Central Europe
- Immune biomarkers in relation to exposure to particulate matter : a cross-sectional survey in 17 cities of Central Europe (en)
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| skos:notation
| - RIV/71009396:_____/00:#0000032!RIV08-MZ0-71009396
|
| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/71009396:_____/00:#0000032
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - immune biomarkers; CESAR study; particulate matter (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Lochman, Ivo
- Lochmanová, Alexandra
- Musial, J.
- Rudnai, P.
- Koppová, K.
- Antova, T.
- Fletcher, T.
- Houthuijs, D.
- Fabiánová, E.
- Steerenberg, P. A.
- Van Loveren, H.
- Lebret, E.
- Armstrong, B.
- Brunekreef, B.
- Durbaca, S.
- Erdei, E.
- Jazwiec-Kanyion, B.
- Leonardi, G.
- Niciu, E. M.
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