About: Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The low molecular weight biodegradable poly(lactide acid) (PLA) was tested as suitable material for encapsulation of bioactive agent into microparticles by the method of emulsification and solvent evaporation at reduced pressure. The attention was focused on the examination of encapsulation capacity for incorporation of a model herbicide. The initial amount of herbicide was altered and parameters characterizing microparticles like encapsulation efficiency, size and shape were evaluated by different methods. Low molecular PLA proved to be a suitable matrix for easy encapsulation of bioactive compounds by the oil-in-water emulsion solvent evaporation method, furthermore without significant changes in particles size. The relative lowest loss of herbicide along with the highest encapsulation efficiency was achieved for the highest initial concentration of herbicide which is close to the critical concentration under which the particles could still be prepared. The low molecular weight biodegradable poly(lactide acid) (PLA) was tested as suitable material for encapsulation of bioactive agent into microparticles by the method of emulsification and solvent evaporation at reduced pressure. The attention was focused on the examination of encapsulation capacity for incorporation of a model herbicide. The initial amount of herbicide was altered and parameters characterizing microparticles like encapsulation efficiency, size and shape were evaluated by different methods. Low molecular PLA proved to be a suitable matrix for easy encapsulation of bioactive compounds by the oil-in-water emulsion solvent evaporation method, furthermore without significant changes in particles size. The relative lowest loss of herbicide along with the highest encapsulation efficiency was achieved for the highest initial concentration of herbicide which is close to the critical concentration under which the particles could still be prepared. (en)
Title	Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles (en)
skos:prefLabel	Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles (en)
skos:notation	RIV/70883521:28610/11:43866050!RIV12-MSM-28610___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0111), P(GAP108/10/0200), S, Z(MSM7088352101)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kucharczyk, Pavel Sedlařík, Vladimír Koutný, Marek
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Tomáše Bati ve Zlíně / Univerzitní institut
http://linked.open...dnocenehoVysledku	199203
http://linked.open...ai/riv/idVysledku	RIV/70883521:28610/11:43866050
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	microparticles, poly(lactide acid), Oil-in-water (O/W) emulsion solvent evaporation method, encapsulation, HPLC, biodegradable copolymer (en)
http://linked.open.../riv/klicoveSlovo	Oil-in-water (O/W) emulsion solvent evaporation method biodegradable copolymer microparticles poly(lactide acid) HPLC encapsulation
http://linked.open...ontrolniKodProRIV	[F8AECE6587B6]
http://linked.open...v/mistoKonaniAkce	Corfu Island
http://linked.open...i/riv/mistoVydani	Rhodes
http://linked.open...i/riv/nazevZdroje	Recent Researches in Geography, Geology, Energy, Environment and Biomedicine - Proc. of the 4th WSEAS Int. Conf. on EMESEG'11, 2nd Int. Conf. on WORLD-GEO'11, 5th Int. Conf. on EDEB'11
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of Polymer Systems Biodegradation study of polymeric materials by combination of advanced methods
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Koutný, Marek Kucharczyk, Pavel Sedlařík, Vladimír Stloukal, Petr
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2011-07-14 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Multifunctional Composite Systems Based on Natural and Synthetic Polymers
number of pages	6 (xsd:int)
http://purl.org/ne...btex#hasPublisher	WSEAS Press (GR)
https://schema.org/isbn	978-1-61804-022-0
http://localhost/t...ganizacniJednotka	28610

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