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rdf:type
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Description
| - Medical-grade polyvinyl chloride was modified with sodium ampicillin in a concentration range from 0 to 5 wt % by solvent casting technique using cyclohexanone and N,N-dimethylformamide. The obtained polymeric systems were characterized by optical microscopy, tensile test, and scanning electron microscopy. In addition, in vitro antibacterial activity against Gram-negative and Gram-positive bacteria were determined by an agar diffusion test. Antibiotic release experiments were performed in distilled water and physiological saline solution, which were monitored by UV-vis spectroscopy. The results showed a crucial role of the solvent on the morphology, antibacterial activity, and releasing characteristic of the ampicillin. Furthermore, a mathematical model was applied to data obtained from release study, to characterize the release kinetics of the ampicillin from the polyvinyl chloride-antibiotic systems.
- Medical-grade polyvinyl chloride was modified with sodium ampicillin in a concentration range from 0 to 5 wt % by solvent casting technique using cyclohexanone and N,N-dimethylformamide. The obtained polymeric systems were characterized by optical microscopy, tensile test, and scanning electron microscopy. In addition, in vitro antibacterial activity against Gram-negative and Gram-positive bacteria were determined by an agar diffusion test. Antibiotic release experiments were performed in distilled water and physiological saline solution, which were monitored by UV-vis spectroscopy. The results showed a crucial role of the solvent on the morphology, antibacterial activity, and releasing characteristic of the ampicillin. Furthermore, a mathematical model was applied to data obtained from release study, to characterize the release kinetics of the ampicillin from the polyvinyl chloride-antibiotic systems. (en)
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Title
| - Antibacterial Polyvinyl Chloride/Antibiotic Films: The Effect of Solvent on Morphology, Antibacterial Activity, and Release Kinetics
- Antibacterial Polyvinyl Chloride/Antibiotic Films: The Effect of Solvent on Morphology, Antibacterial Activity, and Release Kinetics (en)
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skos:prefLabel
| - Antibacterial Polyvinyl Chloride/Antibiotic Films: The Effect of Solvent on Morphology, Antibacterial Activity, and Release Kinetics
- Antibacterial Polyvinyl Chloride/Antibiotic Films: The Effect of Solvent on Morphology, Antibacterial Activity, and Release Kinetics (en)
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skos:notation
| - RIV/70883521:28610/10:63509211!RIV11-MPO-28610___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(2A-1TP1/126), P(MEB090803), Z(MSM7088352101)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/70883521:28610/10:63509211
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - antibacterial properties; antibiotic; polyvinyl chloride; solvent cast; release kinetics. (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Journal of Applied Polymer Science
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Machovský, Michal
- Sedlařík, Vladimír
- Svobodová, Jitka
- Sáha, Petr
- Merchan, Martha
- Sedlaříková, Jana
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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