About: Study of chemical modification of hyaluronic acid     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • The most important mucopolysaccharide, hyaluronic acid (HA), is a linear carbohydrate polymer. Its disaccharide monomeric unit is built up of N-acetyl D-glucosamine and D-glucuronic acid interconnected via b (1#4) and b (1#4) interglycosidic bonds. In aqueous solutions HA forms rigid domains built up from about 10 - 20 monomer units strongly bound by the systém of intra- and inter- molecular hydrogen bonds, thus producing its characteristics of secondary a tertiary configurations. These structures couldbe strongly influenced by insertion on n-alkyl spacers as a branch into this systems. For this reason, five n-alkyl derivatives on the CH2-OH groups of hyaluronic acid, from n-C6- to n-C16- were prepared. The following properties of these products are r eviewed: Kinetic parameters of dissolution, study of enzymatic degradation, thermal analysis and measurements of its electric properties.
  • The most important mucopolysaccharide, hyaluronic acid (HA), is a linear carbohydrate polymer. Its disaccharide monomeric unit is built up of N-acetyl D-glucosamine and D-glucuronic acid interconnected via b (1#4) and b (1#4) interglycosidic bonds. In aqueous solutions HA forms rigid domains built up from about 10 - 20 monomer units strongly bound by the systém of intra- and inter- molecular hydrogen bonds, thus producing its characteristics of secondary a tertiary configurations. These structures couldbe strongly influenced by insertion on n-alkyl spacers as a branch into this systems. For this reason, five n-alkyl derivatives on the CH2-OH groups of hyaluronic acid, from n-C6- to n-C16- were prepared. The following properties of these products are r eviewed: Kinetic parameters of dissolution, study of enzymatic degradation, thermal analysis and measurements of its electric properties. (en)
Title
  • Study of chemical modification of hyaluronic acid
  • Study of chemical modification of hyaluronic acid (en)
skos:prefLabel
  • Study of chemical modification of hyaluronic acid
  • Study of chemical modification of hyaluronic acid (en)
skos:notation
  • RIV/70883521:28110/01:63500362!RIV/2002/MSM/281102/N
http://linked.open.../vavai/riv/strany
  • 89-90
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 265200015)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 697713
http://linked.open...ai/riv/idVysledku
  • RIV/70883521:28110/01:63500362
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hyaluronic acid, chemical modification, polysaccharides (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [A0A1509ABDF5]
http://linked.open...v/mistoKonaniAkce
  • Košice, Slovenská Republika
http://linked.open...i/riv/mistoVydani
  • Košice
http://linked.open...i/riv/nazevZdroje
  • Structure and Stability of Biomacromolecules SSB'01
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Lapčík, Lubomír
  • Benešová, K.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Slovenská akadémia vied; Univerzita Pavla Jozefa Šafárika v Košiciach
http://localhost/t...ganizacniJednotka
  • 28110
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software