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| Description
| - This doctoral thesis presents the study of optical properties of nitrogen-vacancy (NV) centers in variously functionalized fluorescent nanodiamond particles (FND). NV center in diamond is a deep laying point defect which is the diamond bandgap, containing nitrogen and a neighboring vacancy. In this thesis we used the very specific properties of these NV centers engineered in diamond to be used as nanoscale sensors operating in cells. High biocompatibility of nanodiamond, variable FND size ranging from ~ 5 nm, stable luminescence from its NV centers and simple carbon chemistry for biomolecule grafting make FND an attractive alternative to molecular dyes for drug-delivery. This thesis present a principle of a novel method that can be used for remote monitoring of chemical processes in biological environment based on color changes from photo-luminescent (PL) NV centers in FND. It is proposed to drive the NV luminescence chemically, by alternating the surface chemical potential by interacting atoms and molecules with the diamond surface. This leads to changes in NV-/NV0 PL ratio, or in other words the occupation of neutral and negatively charged NV center, and allows construction of optical chemo-biosensors operating in cells, with PL visible in classical confocal microscopes.
- This doctoral thesis presents the study of optical properties of nitrogen-vacancy (NV) centers in variously functionalized fluorescent nanodiamond particles (FND). NV center in diamond is a deep laying point defect which is the diamond bandgap, containing nitrogen and a neighboring vacancy. In this thesis we used the very specific properties of these NV centers engineered in diamond to be used as nanoscale sensors operating in cells. High biocompatibility of nanodiamond, variable FND size ranging from ~ 5 nm, stable luminescence from its NV centers and simple carbon chemistry for biomolecule grafting make FND an attractive alternative to molecular dyes for drug-delivery. This thesis present a principle of a novel method that can be used for remote monitoring of chemical processes in biological environment based on color changes from photo-luminescent (PL) NV centers in FND. It is proposed to drive the NV luminescence chemically, by alternating the surface chemical potential by interacting atoms and molecules with the diamond surface. This leads to changes in NV-/NV0 PL ratio, or in other words the occupation of neutral and negatively charged NV center, and allows construction of optical chemo-biosensors operating in cells, with PL visible in classical confocal microscopes. (en)
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| Title
| - Interactions of nitrogen–vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes
- Interactions of nitrogen–vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes (en)
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| skos:prefLabel
| - Interactions of nitrogen–vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes
- Interactions of nitrogen–vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes (en)
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| skos:notation
| - RIV/68407700:21460/13:00207033!RIV14-MSM-21460___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21460/13:00207033
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - nanodiamond; NV luminescence; biosensor (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
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| http://localhost/t...ganizacniJednotka
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