About: GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat

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About: GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Specific GABAB receptor agonist baclofen is used in clinical practice for the treatment of spasticity but it also exerts an analgesic effect. In this work we describe this effect, which was attenuated in the model of chronic neuropathic pain, probably due to the degeneration of GABA interneurons after chronic constriction injury. Specific GABAB receptor agonist baclofen is used in clinical practice for the treatment of spasticity but it also exerts an analgesic effect. In this work we describe this effect, which was attenuated in the model of chronic neuropathic pain, probably due to the degeneration of GABA interneurons after chronic constriction injury. (en) Specifický agonista GABA(B) receptoru baklofen se vklinické praxi používá při léčbě spasticity, ale má také analgetický efekt. Práce se zabývá analgetickým účinkem baklofenu u modelu chronické neuropatické bolesti. Tento efekt je zde oslaben, pravděpodobně kvůli degeneraci GABA interneuronů vmíše. (cs)
Title	Agonista GABA(B) receptoru baklofen má u modelu periferní neuropatie nespecifický antinocicepční účinek (cs) GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat (en)
skos:prefLabel	Agonista GABA(B) receptoru baklofen má u modelu periferní neuropatie nespecifický antinocicepční účinek (cs) GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat GABA(B) Receptor Agonist Baclofen has Non-specific Antinociceptive Effect in the Model of Peripheral Neuropathy in the Rat (en)
skos:notation	RIV/68407700:21460/04:12141321!RIV08-MSM-21460___
http://linked.open.../vavai/riv/strany	351;355
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(LN00B122), P(NF7406), S, Z(MSM 111200005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Rokyta, Richard Vaculín, Šimon
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	České vysoké učení technické v Praze / Fakulta biomedicínského inženýrství
http://linked.open...dnocenehoVysledku	565138
http://linked.open...ai/riv/idVysledku	RIV/68407700:21460/04:12141321
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	allodynia; cord dorsal horn; hyperalgesia; mechanism; mononeuropathy; neurectomy; pain; pharmacology; sciatic-nerve injury; slices (en)
http://linked.open.../riv/klicoveSlovo	cord dorsal horn sciatic-nerve injury pain allodynia hyperalgesia mononeuropathy neurectomy pharmacology mechanism slices
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[2CD023230B51]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Neuropsychiatric Research Center Antinociceptive mechanisms of motor cortex stimulation.
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Rokyta, Richard Vaculín, Šimon Franěk, M.
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111200005
issn	0862-8408
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	21460

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