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Description
  • This manuscript gives an overview of our team effort to formulate a bone remodelling model that would comprise both crucial control mechanisms in this process: RANKL-RANK-OPG pathway and (dynamic) loading. Main focus is aimed at how model of interdisciplinary problem can be tracked down and how its results and analysis may provide valuable information hopefully not only to mathematicians but to clinicians as well. Modelling is always a theoretical work that is always built upon some simplifications and assumptions which lead to intrinsic limitations of the model that need to be found. Here we provide feasible results that can be obtained through our approach and offer them to discussion.
  • This manuscript gives an overview of our team effort to formulate a bone remodelling model that would comprise both crucial control mechanisms in this process: RANKL-RANK-OPG pathway and (dynamic) loading. Main focus is aimed at how model of interdisciplinary problem can be tracked down and how its results and analysis may provide valuable information hopefully not only to mathematicians but to clinicians as well. Modelling is always a theoretical work that is always built upon some simplifications and assumptions which lead to intrinsic limitations of the model that need to be found. Here we provide feasible results that can be obtained through our approach and offer them to discussion. (en)
Title
  • Feasible prediction of bone remodelling using modelling techniques
  • Feasible prediction of bone remodelling using modelling techniques (en)
skos:prefLabel
  • Feasible prediction of bone remodelling using modelling techniques
  • Feasible prediction of bone remodelling using modelling techniques (en)
skos:notation
  • RIV/68407700:21340/11:00187785!RIV12-MSM-21340___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM6840770010)
http://linked.open...iv/cisloPeriodika
  • 1+2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 199460
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21340/11:00187785
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • bone remodelling; RANKL-RANK-OPG chain; dynamic loading (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [ABA1FEE8F0D0]
http://linked.open...i/riv/nazevZdroje
  • Pohybové ústrojí. Pokroky ve výzkumu, diagnostice a terapii
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 18
http://linked.open...iv/tvurceVysledku
  • Klika, Václav
  • Maršík, F.
http://linked.open...n/vavai/riv/zamer
issn
  • 1212-4575
number of pages
http://localhost/t...ganizacniJednotka
  • 21340
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