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| Description
| - Objective. To assess whether available algorithms of quantitative EEG (qEEG) could practically help in localizing epileptogenic zone (EZ) and modify surgical planning in patients with focal intractable epilepsy. Methods. We will present a case report of a 7-year-old boy with catastrophic epilepsy caused by focal cortical dysplasia located in the operculo-insular region of the right hemisphere. Due to the challenging localization of the presumed EZ, uncertain surgical borders and expected significant risks of the resection, the patient was stereotactically implanted with oblique depth electrodes. Intracranial EEG (iEEG) signal was analyzed using different qEEG methods. Our originally developed interictal epileptiform discharges (IED) detecting algorithm, which also extracts repetitive propagation patterns, was applied to localize sources of IED. We also used own network connectivity algorithm to analyze ictal (seizure) iEEG activity in detail. Employing results of qEEG analyses, 2D and 3D dynamic reconstructions of both interictal and ictal iEEG epileptiform changes were created and used to guide surgical approach. Results. Both qEEG algorithms clearly proved the EZ localization in the dorso-caudal insular cortex of the right hemisphere and demonstrated sparing of initially suspected frontal opercular area. The dorso-caudal insular cortex generated 89% of IED; remaining 11% IED originated from the primary motor cortex. Surgical approach was adjusted to this qEEG-based hypothesis. Oblique depth electrodes were preserved intraoperatively to help precise targeting of the lesion. Continuous intraoperative motor-evoked potential monitoring was used to preserve motor functions. The boy has been followed for more than one year postoperatively. He is seizure-free with no motor deficit; with normal cognitive functions. Conclusions. The case report demonstrates that currently available qEEG methods could help in guiding resective epilepsy surgery in complicated patients indica
- Objective. To assess whether available algorithms of quantitative EEG (qEEG) could practically help in localizing epileptogenic zone (EZ) and modify surgical planning in patients with focal intractable epilepsy. Methods. We will present a case report of a 7-year-old boy with catastrophic epilepsy caused by focal cortical dysplasia located in the operculo-insular region of the right hemisphere. Due to the challenging localization of the presumed EZ, uncertain surgical borders and expected significant risks of the resection, the patient was stereotactically implanted with oblique depth electrodes. Intracranial EEG (iEEG) signal was analyzed using different qEEG methods. Our originally developed interictal epileptiform discharges (IED) detecting algorithm, which also extracts repetitive propagation patterns, was applied to localize sources of IED. We also used own network connectivity algorithm to analyze ictal (seizure) iEEG activity in detail. Employing results of qEEG analyses, 2D and 3D dynamic reconstructions of both interictal and ictal iEEG epileptiform changes were created and used to guide surgical approach. Results. Both qEEG algorithms clearly proved the EZ localization in the dorso-caudal insular cortex of the right hemisphere and demonstrated sparing of initially suspected frontal opercular area. The dorso-caudal insular cortex generated 89% of IED; remaining 11% IED originated from the primary motor cortex. Surgical approach was adjusted to this qEEG-based hypothesis. Oblique depth electrodes were preserved intraoperatively to help precise targeting of the lesion. Continuous intraoperative motor-evoked potential monitoring was used to preserve motor functions. The boy has been followed for more than one year postoperatively. He is seizure-free with no motor deficit; with normal cognitive functions. Conclusions. The case report demonstrates that currently available qEEG methods could help in guiding resective epilepsy surgery in complicated patients indica (en)
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| Title
| - PRACTICAL VALUE OF QUANTITATIVE EEG IN EPILEPSY SURGERY PLANNING
- PRACTICAL VALUE OF QUANTITATIVE EEG IN EPILEPSY SURGERY PLANNING (en)
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| skos:prefLabel
| - PRACTICAL VALUE OF QUANTITATIVE EEG IN EPILEPSY SURGERY PLANNING
- PRACTICAL VALUE OF QUANTITATIVE EEG IN EPILEPSY SURGERY PLANNING (en)
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| skos:notation
| - RIV/68407700:21230/14:00223615!RIV15-MSM-21230___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21230/14:00223615
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - quantitative EEG; assesment; surgery (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Havel, Tomáš
- Ježdík, Petr
- Čmejla, Roman
- Janča, Radek
- Tichý, M.
- Kršek, P.
- Jiruška, P.
- Marusič, P.
- Komárek, V.
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| http://localhost/t...ganizacniJednotka
| |
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