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| rdf:type
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| Description
| - The identification of atrial fibrillation (AF) substrates is needed to improve ablation therapy guided by electrograms (EGM), although mechanisms that sustain AF are not fully understood. Detection of complex fractionated atrial electrograms (CFAE) is used for this purpose. Nonetheless, efficacy of this method is poor in the case of chronic AF. Recent hypothesis proposes the rotors as fibrillatory substrate. Novel approaches seek to relate CFAE with rotor; nevertheless, such methods are not able to identify the associated substrate. Furthermore, the patterns that characterize CFAE generated by rotors remain unknown. Thus, tracking of rotors is an unsolved issue. In this paper we propose a non-supervised method to find patterns associated with fibrillatory substrates in chronic AF. We extracted two features based on local activation wave detection and one feature based on non-linear dynamics. Gaussian mixture model-based clustering was used to discriminate CFAE patterns. Resulting clusters were visualized in an electroanatomic map. We assessed the proposed method in a real database labeled according to the level of fractionation and in a simulated episode of chronic AF in which a rotor was detected. Our results indicate that the method proposed is able to separate different levels of fractionation in CFAE, and provide evidence that clustering can be used to locate the vortex of the rotors. Such method can aid ablation therapy procedures by means of CFAE patterns discrimination.
- The identification of atrial fibrillation (AF) substrates is needed to improve ablation therapy guided by electrograms (EGM), although mechanisms that sustain AF are not fully understood. Detection of complex fractionated atrial electrograms (CFAE) is used for this purpose. Nonetheless, efficacy of this method is poor in the case of chronic AF. Recent hypothesis proposes the rotors as fibrillatory substrate. Novel approaches seek to relate CFAE with rotor; nevertheless, such methods are not able to identify the associated substrate. Furthermore, the patterns that characterize CFAE generated by rotors remain unknown. Thus, tracking of rotors is an unsolved issue. In this paper we propose a non-supervised method to find patterns associated with fibrillatory substrates in chronic AF. We extracted two features based on local activation wave detection and one feature based on non-linear dynamics. Gaussian mixture model-based clustering was used to discriminate CFAE patterns. Resulting clusters were visualized in an electroanatomic map. We assessed the proposed method in a real database labeled according to the level of fractionation and in a simulated episode of chronic AF in which a rotor was detected. Our results indicate that the method proposed is able to separate different levels of fractionation in CFAE, and provide evidence that clustering can be used to locate the vortex of the rotors. Such method can aid ablation therapy procedures by means of CFAE patterns discrimination. (en)
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| Title
| - Fractionated Electrograms and Rotors Detection in Chronic Atrial Fibrillation Using Model-Based Clustering
- Fractionated Electrograms and Rotors Detection in Chronic Atrial Fibrillation Using Model-Based Clustering (en)
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| skos:prefLabel
| - Fractionated Electrograms and Rotors Detection in Chronic Atrial Fibrillation Using Model-Based Clustering
- Fractionated Electrograms and Rotors Detection in Chronic Atrial Fibrillation Using Model-Based Clustering (en)
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| skos:notation
| - RIV/68407700:21230/14:00221648!RIV15-GA0-21230___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/68407700:21230/14:00221648
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Databases; Entropy; Feature Extraction; Fractionation; Medical Services; Rotors; Substrates (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...v/mistoKonaniAkce
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...i/riv/nazevZdroje
| - Proceedings of 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Křemen, Václav
- Novák, Daniel
- Bustamante, J.
- Orozco-Duque, A.
- Saiz, J.
- Ugarte, J. P.
- Castellanos-Dominguez, G.
- Duque, S. I.
- Tobon, C.
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| http://linked.open...vavai/riv/typAkce
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| http://linked.open.../riv/zahajeniAkce
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| number of pages
| |
| http://bibframe.org/vocab/doi
| - 10.1109/EMBC.2014.6943905
|
| http://purl.org/ne...btex#hasPublisher
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| https://schema.org/isbn
| |
| http://localhost/t...ganizacniJednotka
| |
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