About: Correlation of Dynamic Impact Testing, Histopathology and Visual Macroscopic Assessment in Human Osteoarthritic Cartilage     Goto   Sponge   NotDistinct   Permalink

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Description
  • Objective Improved staging of cartilage degeneration is required, particularly during the early stages. We correlated mechanical properties with histological and macroscopic findings. Methods One hundred and twenty cartilage samples were obtained during total knee arthroplasty. Two adjacent plugs were harvested-one for histological classification and one for macroscopic and biomechanical purposes. Dynamic impact testing was performed; normal stress, dissipated energy (ΔE), tangent modulus and stiffness were evaluated. Results Samples were classified according to six categories of the ICRS histological scale. Mechanical characteristics revealing significant differences between the groups (p<0.01) were specific damping and related absolute ΔE. A significant correlation was found between the macroscopic score and specific damping, as well as absolute and relative ΔE (p<0.01). A strong relation was revealed between relative ΔE and cartilage thickness (p< 0.001; R2
  • Objective Improved staging of cartilage degeneration is required, particularly during the early stages. We correlated mechanical properties with histological and macroscopic findings. Methods One hundred and twenty cartilage samples were obtained during total knee arthroplasty. Two adjacent plugs were harvested-one for histological classification and one for macroscopic and biomechanical purposes. Dynamic impact testing was performed; normal stress, dissipated energy (ΔE), tangent modulus and stiffness were evaluated. Results Samples were classified according to six categories of the ICRS histological scale. Mechanical characteristics revealing significant differences between the groups (p<0.01) were specific damping and related absolute ΔE. A significant correlation was found between the macroscopic score and specific damping, as well as absolute and relative ΔE (p<0.01). A strong relation was revealed between relative ΔE and cartilage thickness (p< 0.001; R2 (en)
Title
  • Correlation of Dynamic Impact Testing, Histopathology and Visual Macroscopic Assessment in Human Osteoarthritic Cartilage
  • Correlation of Dynamic Impact Testing, Histopathology and Visual Macroscopic Assessment in Human Osteoarthritic Cartilage (en)
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  • Correlation of Dynamic Impact Testing, Histopathology and Visual Macroscopic Assessment in Human Osteoarthritic Cartilage
  • Correlation of Dynamic Impact Testing, Histopathology and Visual Macroscopic Assessment in Human Osteoarthritic Cartilage (en)
skos:notation
  • RIV/68407700:21230/11:00176130!RIV13-MSM-21230___
http://linked.open...avai/riv/aktivita
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  • I, P(FI-IM4/205), P(FT-TA5/020), Z(MSM6840770012)
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  • 1
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  • 192053
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  • RIV/68407700:21230/11:00176130
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  • Osteoarthritic cartilage; dynamic impact testin; correlation (en)
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  • DE - Spolková republika Německo
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  • [59CD9726BE78]
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  • International Orthopaedics
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http://linked.open...v/svazekPeriodika
  • 35
http://linked.open...iv/tvurceVysledku
  • Almer, E.
  • Chudáček, Václav
  • Držík, M.
  • Handl, M.
  • Hanus, M.
  • Kautzner, J.
  • Kos, P.
  • Povýšil, C.
  • Trč, T.
  • Varga, F.
http://linked.open...ain/vavai/riv/wos
  • 000295982400021
http://linked.open...n/vavai/riv/zamer
issn
  • 0341-2695
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00264-010-1195-1
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  • 21230
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