About: Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants     Goto   Sponge   NotDistinct   Permalink

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Description
  • A several metallic materials with different surface treatments (machined pure Ti and Ti6Al4V, polished Ti and Ti6Al4V, and Ti5Al2.5Fe treated by electroerosion and plasma-sprayed with Ti) were seeded with human osteoblast-like cells MG 63. After one day, the highest cell numbers were obtained on the samples of medium surface roughness (T and TS; Ra 0.63:0.30 um and 0.89:0.57 um, respectively). From day 1 to 4, the cell proliferation was the quickest on the samples with the lowest surface roughness (TL and TSL; Ra 0.17:0.13 for both materials). The cells on TL also contained the highest concentration of integrin adhesion molecules with alpha V chain, i.e. receptors for vitronectin and fibronectin. On day 8 after seeding, the cells on all metallic samples and polystyrene reached similar population densities.
  • A several metallic materials with different surface treatments (machined pure Ti and Ti6Al4V, polished Ti and Ti6Al4V, and Ti5Al2.5Fe treated by electroerosion and plasma-sprayed with Ti) were seeded with human osteoblast-like cells MG 63. After one day, the highest cell numbers were obtained on the samples of medium surface roughness (T and TS; Ra 0.63:0.30 um and 0.89:0.57 um, respectively). From day 1 to 4, the cell proliferation was the quickest on the samples with the lowest surface roughness (TL and TSL; Ra 0.17:0.13 for both materials). The cells on TL also contained the highest concentration of integrin adhesion molecules with alpha V chain, i.e. receptors for vitronectin and fibronectin. On day 8 after seeding, the cells on all metallic samples and polystyrene reached similar population densities. (en)
  • Série kovových materiálů s různými povrchovými úpravami byla připravená: čistý obrobený strojem titan (T), titan leštěný diamantovou pastou (TL), obrobená strojem Ti6Al4V slitina (TS), Ti6Al4V slitina leštěný diamantovou pastou (TSL), Ti5Al2.5Fe slitina ošetřený elektrolyticky pokovuje-erozi (A) a Ti5Al2.5Fe plazma-nastříkat Ti (PL). Materiály byly nasazené s lidský osteoblast-jako buňky MG 63. Jednoho dne po očkování. Buňky na TL také obsahovaly nejvyšší soustřeďování integrity soudržnost molekulový s abecední V řetězu, to jest příjemce pro vitronectin a fibronectin. Buňky na elektrolyticky pokovují-erodované Ti5Al2.5Fe (vzorky ; Ra 15.27+-0.74 um) obsahoval nejvyšší soustřeďování osteocalcin a osteopontin, to jest ukazovatelé osteoblast derivování. Tak, pozdější nově rozvinutý materiál mohl byl považován jak slibný pro stavět kost zasadit dobře kotvený v okolní kosti tkanina. (cs)
Title
  • Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants
  • Adhese, růst a diferenciace markerů buněk podobných lidským osteoblastům pěstovaným na povrchově modifikovaných površích kovových materiálů, určených pro umělé náhrady kostí (cs)
  • Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants (en)
skos:prefLabel
  • Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants
  • Adhese, růst a diferenciace markerů buněk podobných lidským osteoblastům pěstovaným na povrchově modifikovaných površích kovových materiálů, určených pro umělé náhrady kostí (cs)
  • Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants (en)
skos:notation
  • RIV/68407700:21220/06:02142684!RIV08-GA0-21220___
http://linked.open.../vavai/riv/strany
  • 1;3
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA101/06/0226), Z(MSM6840770012)
http://linked.open...iv/cisloPeriodika
  • 58-60
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 464178
http://linked.open...ai/riv/idVysledku
  • RIV/68407700:21220/06:02142684
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ti alloys; adhesion; bone cells; osteocalcin; proliferation; surface roughness; titanium (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [E08BD4A0760E]
http://linked.open...i/riv/nazevZdroje
  • Inžynieria Biomaterialów
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Lisá, V.
  • Starý, Vladimír
  • Bačáková, L.
  • Kabátová, J.
  • Fencl, J.
http://linked.open...n/vavai/riv/zamer
issn
  • 1429-7248
number of pages
http://localhost/t...ganizacniJednotka
  • 21220
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