About: First results on cell irradiation with laser-driven protons on the TARANIS system

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen’s University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 109 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.40.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source. The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen’s University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 109 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.40.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source. (en)
Title	First results on cell irradiation with laser-driven protons on the TARANIS system First results on cell irradiation with laser-driven protons on the TARANIS system (en)
skos:prefLabel	First results on cell irradiation with laser-driven protons on the TARANIS system First results on cell irradiation with laser-driven protons on the TARANIS system (en)
skos:notation	RIV/68378271:_____/13:00420820!RIV14-MSM-68378271
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED1.1.00/02.0061), P(EE.2.3.20.0087)
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Borghesi, Marco
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	75211
http://linked.open...ai/riv/idVysledku	RIV/68378271:_____/13:00420820
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	TARANIS Terawatt laser; proton irradiation; radiobiological studies; cells (en)
http://linked.open.../riv/klicoveSlovo	TARANIS Terawatt laser radiobiological studies cells proton irradiation
http://linked.open...ontrolniKodProRIV	[C8B4B3ED452F]
http://linked.open...v/mistoKonaniAkce	Catania
http://linked.open...i/riv/mistoVydani	Melville
http://linked.open...i/riv/nazevZdroje	2nd ELIMED Workshop and Panel
http://linked.open...in/vavai/riv/obor	BL
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	18 (xsd:int)
http://linked.open...vavai/riv/projekt	ELI: EXTREME LIGHT INFRASTRUCTURE RESEARCH AND DEVELOPMENT OF NEW WAYS OF RADIATION GENERATION AND CHARGED PARTICLES BY ULTRA-INTENSE LASER FIELDS
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Prasad, R. Borghesi, Marco Doria, D. Kakolee, K. F. Kar, S. Zepf, M. Schettino, G. Ahmed, H. Fiorini, F. Green, S. Jeynes, J.C.G. Kirby, D. Kirkby, K. J. Lewis, C. Litt, S. Merchant, M. J. Nersisyan, G. Prise, K. M.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open...ain/vavai/riv/wos	000324289100013
http://linked.open.../riv/zahajeniAkce	2012-10-18 (xsd:date)
number of pages	3 (xsd:int)
http://bibframe.org/vocab/doi	10.1063/1.4816612
http://purl.org/ne...btex#hasPublisher	AIP
https://schema.org/isbn	978-0-7354-1171-5

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