About: Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats     Goto   Sponge   NotDistinct   Permalink

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  • Fumaric acid esters (FAE) exhibit immunomodulatory, anti-inflammatory, and anti-oxidative effects. We tested protective effects of FAE treatment in an animal model of inflammation and metabolic syndrome, the spontaneously hypertensive rat transgenically expressing human C-reactive protein (SHR-CRP). Our results provided evidence for important anti-inflammatory, anti-oxidative, and metabolic effects of FAE in SHR-CRP rats
  • Fumaric acid esters (FAE) exhibit immunomodulatory, anti-inflammatory, and anti-oxidative effects. We tested protective effects of FAE treatment in an animal model of inflammation and metabolic syndrome, the spontaneously hypertensive rat transgenically expressing human C-reactive protein (SHR-CRP). Our results provided evidence for important anti-inflammatory, anti-oxidative, and metabolic effects of FAE in SHR-CRP rats (en)
Title
  • Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats
  • Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats (en)
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  • Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats
  • Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats (en)
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  • RIV/68378050:_____/14:00431291!RIV15-AV0-68378050
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  • I, P(LH12061), P(LL1204)
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  • 7
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  • 17643
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  • RIV/68378050:_____/14:00431291
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  • fumaric acid esters; C-reactive protein; transgenic; spontaneously hypertensive rat (en)
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  • US - Spojené státy americké
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  • [03103047DDA5]
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  • PLoS ONE
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  • 9
http://linked.open...iv/tvurceVysledku
  • Kazdová, L.
  • Landa, Vladimír
  • Mlejnek, Petr
  • Pravenec, Michal
  • Strnad, Hynek
  • Zídek, Václav
  • Šimáková, Miroslava
  • Oliyarnyk, O.
  • Šilhavý, Jan
  • Škop, V.
  • Kurtz, T.
http://linked.open...ain/vavai/riv/wos
  • 000338763800051
issn
  • 1932-6203
number of pages
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  • 10.1371/journal.pone.0101906
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