About: New insight into transcription of human endogenous retroviral elements

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: New insight into transcription of human endogenous retroviral elements Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	It is generally assumed that human endogenous retroviral elements (HERVs) belong to the class of genomic repetitive nucleotide sequences often called junk DNA’. These elements were categorized to families, and members of some of these families (e.g. HERV-H, HERV-W and HERV-K) were shown to be transcribed. These transcriptions were associated with several severe diseases such as mental disorders, AIDS, autoimmune diseases and cancer. In this review we discuss several bioinformatics strategies for genome-wide scan of HERVs transcription using high-throughput RNA sequencing on several platforms. We show that many more HERVs than previously described are transcribed to various levels and we discuss possible implications of these transcriptions. It is generally assumed that human endogenous retroviral elements (HERVs) belong to the class of genomic repetitive nucleotide sequences often called junk DNA’. These elements were categorized to families, and members of some of these families (e.g. HERV-H, HERV-W and HERV-K) were shown to be transcribed. These transcriptions were associated with several severe diseases such as mental disorders, AIDS, autoimmune diseases and cancer. In this review we discuss several bioinformatics strategies for genome-wide scan of HERVs transcription using high-throughput RNA sequencing on several platforms. We show that many more HERVs than previously described are transcribed to various levels and we discuss possible implications of these transcriptions. (en)
Title	New insight into transcription of human endogenous retroviral elements New insight into transcription of human endogenous retroviral elements (en)
skos:prefLabel	New insight into transcription of human endogenous retroviral elements New insight into transcription of human endogenous retroviral elements (en)
skos:notation	RIV/68378050:_____/13:00394696!RIV13-GA0-68378050
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GCP305/10/J052)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Pačes, Václav Pačes, Jan Rídl, Jakub
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	91594
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/13:00394696
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	HERV; transcription; tissue-specific (en)
http://linked.open.../riv/klicoveSlovo	HERV tissue-specific transcription
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[C2D98A135E3D]
http://linked.open...i/riv/nazevZdroje	New Biotechnology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Functional analysis of endogenous retroviral elements in human genome: possible association with cancers
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Pačes, Jan Pačes, Václav Rídl, Jakub Chang, C. M. Huang, Y. T.
http://linked.open...ain/vavai/riv/wos	000317240000010
issn	1871-6784
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.nbt.2012.11.009

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software