About: Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8334280.PN.&OS=PN/8334280&RS=PN/8334280
Description	The invention relates to novel ligands of the estrogen receptors α and β of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for the treatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention. The invention relates to novel ligands of the estrogen receptors α and β of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for the treatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention. (en)
Title	Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them (en)
skos:prefLabel	Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them (en)
skos:notation	RIV/68378050:_____/12:00388664!RIV13-AV0-68378050
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z40550506), Z(AV0Z50520514)
http://linked.open...cisloPatentuVzoru	US8334280
http://linked.open...eleniPatentuVzoru	2012-12-18 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Bartůněk, Petr Sedlák, David
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	147050
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/12:00388664
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	estrogen receptor ligand; hormone therapy; cancer therapy (en)
http://linked.open.../riv/klicoveSlovo	estrogen receptor ligand hormone therapy cancer therapy
http://linked.open...ontrolniKodProRIV	[5771BE39E9E6]
http://linked.open...ydaniPatentuVzoru	Alexandria
http://linked.open...atelePatentuVzoru	United States Patent and Trademark Office (USPTO)
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...ydaniPatentuVzoru	US - Spojené státy americké
http://linked.open...iv/tvurceVysledku	Bartůněk, Petr Kotora, Martin Novák, P. Sedlák, David
http://linked.open...mniOchranaPatentu	B - USTPO (Úřad pro patenty a ochranné známky USA)
http://linked.open...avai/riv/vlastnik	Ústav molekulární genetiky AV ČR, v. v. i. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Přírodovědecká fakulta UK v Praze
http://linked.open...itiJinymSubjektem	N - Nabytí licence není nutné (výsledek není licencován)
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
http://linked.open...stnikPatentuVzoru	Ústav molekulární genetiky AV ČR, v. v. i. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Přírodovědecká fakulta UK v Praze

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software