About: Dendritic cell-based vaccines for the therapy of experimental tumors

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Dendritic cells (DCs ), potent antigen-presenting cells (APC) are able to link the innate and adaptive immune system. Many studies have been focused on different immunotherapeutic approaches to apply DCs as tools improving anticancer therapy. Although the benefit of DC-based vaccination during anticancer therapy have been reported, the general knowledge about the ultimate methods of DC-vaccine preparation still remains unsatisfied. Additionally, some remote effects of different forms of DC-vaccine application require broader elaboration using animal model studies. This review summarizes the effects of the application of antigen-stimulated and/or genetically modified DCs used as vaccines for the treatment of experimental tumors. Dendritic cells (DCs ), potent antigen-presenting cells (APC) are able to link the innate and adaptive immune system. Many studies have been focused on different immunotherapeutic approaches to apply DCs as tools improving anticancer therapy. Although the benefit of DC-based vaccination during anticancer therapy have been reported, the general knowledge about the ultimate methods of DC-vaccine preparation still remains unsatisfied. Additionally, some remote effects of different forms of DC-vaccine application require broader elaboration using animal model studies. This review summarizes the effects of the application of antigen-stimulated and/or genetically modified DCs used as vaccines for the treatment of experimental tumors. (en)
Title	Dendritic cell-based vaccines for the therapy of experimental tumors Dendritic cell-based vaccines for the therapy of experimental tumors (en)
skos:prefLabel	Dendritic cell-based vaccines for the therapy of experimental tumors Dendritic cell-based vaccines for the therapy of experimental tumors (en)
skos:notation	RIV/68378050:_____/10:00376190!RIV12-MZ0-68378050
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/09/1024), P(IAA500520807), P(NS10660), Z(AV0Z50520514)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Indrová, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	253284
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/10:00376190
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	dendritic cells; preparation of vaccines; experimental tumors (en)
http://linked.open.../riv/klicoveSlovo	dendritic cells experimental tumors preparation of vaccines
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[BD288559B7EF]
http://linked.open...i/riv/nazevZdroje	Immunotherapy
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of experimental vaccine against WT 1 for immunotherapy of tumors Molecular and cellular mechanisms of tumour chemotherapy: immunomodulatory effects Mechanisms of protective immunity against tumours with different expression of immunodulatory molecules
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	2
http://linked.open...iv/tvurceVysledku	Indrová, Marie Piasecka, E. P.
http://linked.open...ain/vavai/riv/wos	000275924300014
http://linked.open...n/vavai/riv/zamer	Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
issn	1750-743X
number of pages	12 (xsd:int)
http://bibframe.org/vocab/doi	10.2217/IMT.10.7

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