About: Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis

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About: Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	It is well known that saccharides and their glycoconjugates can have an important influence on various serious pathologic stages such as cancer. They can regulate tumor proliferation, invasion, hematogenous metastasis, and angiogenesis. These facts clearly show the importance of cancer saccharide recognition. In medicine, sensor analysis is one of the best methods for recognition and determination of biologically important analytes. The development and study of sensors for saccharide tumor markers can open a new way for their detection. Therefore, this review is focused on recognition of saccharide-based cancer markers by natural or synthetic selective ligands working as bio- and chemosensors. The design and application of these ligands for cancer diagnosis is a useful direction of research. Moreover, it also opens the possibility of using these agents for the targeted drug transport required for advanced anticancer therapy. It is well known that saccharides and their glycoconjugates can have an important influence on various serious pathologic stages such as cancer. They can regulate tumor proliferation, invasion, hematogenous metastasis, and angiogenesis. These facts clearly show the importance of cancer saccharide recognition. In medicine, sensor analysis is one of the best methods for recognition and determination of biologically important analytes. The development and study of sensors for saccharide tumor markers can open a new way for their detection. Therefore, this review is focused on recognition of saccharide-based cancer markers by natural or synthetic selective ligands working as bio- and chemosensors. The design and application of these ligands for cancer diagnosis is a useful direction of research. Moreover, it also opens the possibility of using these agents for the targeted drug transport required for advanced anticancer therapy. (en)
Title	Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis (en)
skos:prefLabel	Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis Selective recognition of a saccharide-type tumor marker with natural and synthetic ligands: a new trend in cancer diagnosis (en)
skos:notation	RIV/68378050:_____/10:00356081!RIV11-GA0-68378050
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(GA203/09/1311), P(KAN200200651), P(LC06077), P(LC512), Z(AV0Z50520514), Z(MSM6046137307)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Králová, Jarmila
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	286804
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/10:00356081
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	extracellular-matrix components; hepatocellular carcinoma; breast cancer (en)
http://linked.open.../riv/klicoveSlovo	breast cancer hepatocellular carcinoma extracellular-matrix components
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[E51E682BA6F8]
http://linked.open...i/riv/nazevZdroje	Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Applied Genomics Synthetic probes for recognition of tumor markers:applications for cell directed apoptosis and targeted photodynamic therapy Nanoparticulate and supramolecular systems for targeted drug delivery Center for biomolecules and complex molecular systems Center of Chemical Genetics
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	398
http://linked.open...iv/tvurceVysledku	Bříza, T. Kejík, Z. Král, V. Králová, Jarmila Martásek, P.
http://linked.open...ain/vavai/riv/wos	000283244500005
http://linked.open...n/vavai/riv/zamer	Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů Physico-chemical methods of analysis and characterization of chemical systems and biosystems
issn	1618-2642
number of pages	6 (xsd:int)

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