About: Pax genes in eye development and evolution

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Pax genes in eye development and evolution Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Oči zvířat se liší z anatomického hlediska. Proto se předpokládalo, že vznikly nezávisle několikrát v průběhu evoluce. Objev genu Pax6 zhruba před deseti lety ale všechny tyto argumenty zpochybnil. Od té doby se objevilo více důkazů pro opakované použití genu Pax6 a některých dalších regulátorů používaných pro genetický program vývoje oka. Nedávný výzkum ukázal, že i některé další geny rodiny Pax hrají klíčovou roli v morfogenezi oka. (cs) Animal eyes with widely different anatomical designs have long been thought to arise independently, multiple times during evolution. This view was challenged about a decade ago by the landmark discoveries that Pax6, a highly conserved transcription factor, plays a key role in eye morphogenesis in both flies and mammals. Since then, more evidence has emerged in favour of the redeployment of Pax6 and some other developmental control genes within the genetic program underlying eye formation throughout the animal kingdom. Recent work has indicated that other members of the Pax gene family play a pivotal role in eye morphogenesis. The Eye gone gene regulates eye growth in Drosophila, whereas the PaxB gene is implicated in visual system development in jellyfish, the most basal organism possessing eyes. Animal eyes with widely different anatomical designs have long been thought to arise independently, multiple times during evolution. This view was challenged about a decade ago by the landmark discoveries that Pax6, a highly conserved transcription factor, plays a key role in eye morphogenesis in both flies and mammals. Since then, more evidence has emerged in favour of the redeployment of Pax6 and some other developmental control genes within the genetic program underlying eye formation throughout the animal kingdom. Recent work has indicated that other members of the Pax gene family play a pivotal role in eye morphogenesis. The Eye gone gene regulates eye growth in Drosophila, whereas the PaxB gene is implicated in visual system development in jellyfish, the most basal organism possessing eyes. (en)
Title	Pax genes in eye development and evolution Geny Pax ve vývoji oka a v evoluci (cs) Pax genes in eye development and evolution (en)
skos:prefLabel	Pax genes in eye development and evolution Geny Pax ve vývoji oka a v evoluci (cs) Pax genes in eye development and evolution (en)
skos:notation	RIV/68378050:_____/05:00022522!RIV06-AV0-68378050
http://linked.open.../vavai/riv/strany	430;438
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(GA204/04/1358), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Kozmik, Zbyněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	535568
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/05:00022522
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	paxpax; eye development; evolution (en)
http://linked.open.../riv/klicoveSlovo	evolution eye development paxpax
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[6559329D7566]
http://linked.open...i/riv/nazevZdroje	Current Opinion in Genetics & Development
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Applied Genomics The role of wnt signalling in eye development and lens cell differentiation
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	15
http://linked.open...iv/tvurceVysledku	Kozmik, Zbyněk
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0959-437X
number of pages	9 (xsd:int)

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 77 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software