| Attributes | Values |
|---|
| rdf:type
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| Description
| - Klonovali jsme kuřecí tva cDNA ze dvou linií kuřat náchylných vůči podskupině A ASLV, linii H6 a linii 0. Byly získány dva typy kuřecí tva(s) cDNA. Tyto cDNA kódují delší a kratší formu receptoru Tva homologní s Tva formami u křepelky. Byly identifikovány dva různé defekty v cDNA klonované ze dvou různých inbredních kuřat odolných vůči ASLV(A), linie C a linie 7(2). Linie C tva(r) obsahuje substituci jednoho páru bazí, což vede ke změně cysteinu na tryptofan v oblasti Tva podobné LDLR. Tato mutace drasticky snižuje afinitu Tva(R) k obalovým glykoproteinům ASLV(A). Linie 7(2)tva(r2) obsahuje inzerci 4 bp do exonu 1 způsobující změnu čtecího rámce, která blokuje expresi receptoru Tva (cs)
- We cloned the chicken tva cDNAs from two lines of subgroup A-susceptible chickens, line H6 and line 0. Two types of chicken tva(s) cDNAs were obtained. These cDNAs encode a longer and shorter form of the Tva receptor homologous to the Tva forms in quail. Two different defects were identified in cDNAs cloned from two different ASLV(A)-resistant inbred chickens, line C and line 7(2). Line C tva(r) contains a single base pair substitution, resulting in a cysteine-to-tryptophan change in the LDLR-like region of Tva. This mutation drastically reduces the binding affinity of Tva(R) for the ASLV(A) envelope glycoproteins. Line 7(2)tva(r2) contains a 4-bp insertion in exon 1 that causes a change in the reading frame, which blocks expression of the Tva receptor
- We cloned the chicken tva cDNAs from two lines of subgroup A-susceptible chickens, line H6 and line 0. Two types of chicken tva(s) cDNAs were obtained. These cDNAs encode a longer and shorter form of the Tva receptor homologous to the Tva forms in quail. Two different defects were identified in cDNAs cloned from two different ASLV(A)-resistant inbred chickens, line C and line 7(2). Line C tva(r) contains a single base pair substitution, resulting in a cysteine-to-tryptophan change in the LDLR-like region of Tva. This mutation drastically reduces the binding affinity of Tva(R) for the ASLV(A) envelope glycoproteins. Line 7(2)tva(r2) contains a 4-bp insertion in exon 1 that causes a change in the reading frame, which blocks expression of the Tva receptor (en)
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| Title
| - Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses
- Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses (en)
- Dva různé molekulární defekty genu pro receptor Tva vysvětlují odolnost dvou kuřecích linií tvar vůči infekci ptačími sarkomovými a leukózovými viry (cs)
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| skos:prefLabel
| - Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses
- Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses (en)
- Dva různé molekulární defekty genu pro receptor Tva vysvětlují odolnost dvou kuřecích linií tvar vůči infekci ptačími sarkomovými a leukózovými viry (cs)
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| skos:notation
| - RIV/68378050:_____/04:00105374!RIV/2005/AV0/A23005/N
|
| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(GA523/04/0489), P(KSK5011112), Z(AV0Z5052915)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/68378050:_____/04:00105374
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - ASLV; retrovirus receptor (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Svoboda, Jan
- Trejbalová, Kateřina
- Elleder, Daniel
- Federspiel, M.
- Melder, D. C.
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| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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