About: MHC class I down-regulation: Tumour escape from immune surveillance? (Review)     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Předpokládá se, že snížená exprese MHC 1. třídy může za určitých okolností být mechanismem pro únik nádorů před imunitní obranou. Měly by být zváženy léčebné postupy zaměřené na zvýšení exprese MHC 1. třídy či na posílení efektorových mechanismů obrany proti nádorům neomezeným MHC 1. třídy (CD4+, NK, NKT, gama-delta T), nebo na využití geneticky modifikovaných nádorových vakcín založených na genech pro cytokiny (cs)
  • It is suggested that MHC class I down-regulation can, under some conditions, be a mechanism of the tumour escape from the immune defence. The therapeutic procedures aiming at up-regulation of MHC class I expression, or enhancement of MHC class I-unrestricted (CD4+, NK, NKT, gamma-delta T) tumour defence effector mechanisms by dendritic cell-based therapeutic vaccines, by cytokines (IL-2, IL-12, IFNgamma, GM-CSF), or by the cytokine gene-based, genetically modified tumour vaccines should be considered
  • It is suggested that MHC class I down-regulation can, under some conditions, be a mechanism of the tumour escape from the immune defence. The therapeutic procedures aiming at up-regulation of MHC class I expression, or enhancement of MHC class I-unrestricted (CD4+, NK, NKT, gamma-delta T) tumour defence effector mechanisms by dendritic cell-based therapeutic vaccines, by cytokines (IL-2, IL-12, IFNgamma, GM-CSF), or by the cytokine gene-based, genetically modified tumour vaccines should be considered (en)
Title
  • MHC class I down-regulation: Tumour escape from immune surveillance? (Review)
  • MHC class I down-regulation: Tumour escape from immune surveillance? (Review) (en)
  • Snížená exprese MHC 1. třídy: únik nádorů z imunitní kontroly? (cs)
skos:prefLabel
  • MHC class I down-regulation: Tumour escape from immune surveillance? (Review)
  • MHC class I down-regulation: Tumour escape from immune surveillance? (Review) (en)
  • Snížená exprese MHC 1. třídy: únik nádorů z imunitní kontroly? (cs)
skos:notation
  • RIV/68378050:_____/04:00105304!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany
  • 487;491
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA301/04/0492), P(IAA5052203), P(NC7148), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 573448
http://linked.open...ai/riv/idVysledku
  • RIV/68378050:_____/04:00105304
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • MHC class I- tumour cells; immune surveillance (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GR - Řecká republika
http://linked.open...ontrolniKodProRIV
  • [54ACD5471BF6]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Oncology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Bubeník, Jan
http://linked.open...n/vavai/riv/zamer
issn
  • 1019-6439
number of pages
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 77 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software