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  • The aim of this review was to evaluate the results of IL-2 therapy of cancer two decades after the first experiments and to discuss whether and which results of local, systemic and adjuvant IL-2 therapy in preclinical models can be translated into clinics. The attention was also focused on the development and utilization of the IL-2 gene-modified tumour vaccines for therapeutic purposes. The prospects and limitations of both, IL-2 therapy and IL-2 gene therapy were discussed
  • The aim of this review was to evaluate the results of IL-2 therapy of cancer two decades after the first experiments and to discuss whether and which results of local, systemic and adjuvant IL-2 therapy in preclinical models can be translated into clinics. The attention was also focused on the development and utilization of the IL-2 gene-modified tumour vaccines for therapeutic purposes. The prospects and limitations of both, IL-2 therapy and IL-2 gene therapy were discussed (en)
  • Cílem tohoto přehledného článku bylo zhodnotit výsledky léčby nádorů pomocí IL-2 dvě desetiletí po prvních experimentech a rozebrat, zda a které výsledky lokální, systémové a adjuvantní léčby IL-2 v preklinických modelech lze převést do klinické praxe. Pozornost byla též zaměřena na vývoj a využití nádorových vakcín modifikovaných genem pro IL-2 k léčebným účelům. Byly rozebrány perspektivy a omezení léčby IL-2 i genové léčby IL-2 (cs)
Title
  • Interleukin-2 Therapy of Cancer
  • Interleukin-2 Therapy of Cancer (en)
  • Léčba rakoviny pomocí IL-2 (cs)
skos:prefLabel
  • Interleukin-2 Therapy of Cancer
  • Interleukin-2 Therapy of Cancer (en)
  • Léčba rakoviny pomocí IL-2 (cs)
skos:notation
  • RIV/68378050:_____/04:00105303!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany
  • 120;130
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA301/04/0492), P(IAA5052203), P(NC7148), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika
  • 3-4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 568663
http://linked.open...ai/riv/idVysledku
  • RIV/68378050:_____/04:00105303
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • interleukin 2; cancer therapy (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [FFDD94AD3B1E]
http://linked.open...i/riv/nazevZdroje
  • Folia Biologica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 50
http://linked.open...iv/tvurceVysledku
  • Bubeník, Jan
http://linked.open...n/vavai/riv/zamer
issn
  • 0015-5500
number of pages
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