About: Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells     Goto   Sponge   NotDistinct   Permalink

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Description
  • In epithelial cells, the cell surface glycoprotein E-cadherin is a key molecule in the establishment of cell-cell adhesion. In addition to its contribution to cell adhesion, E-cadherin was found to induce ligand-independent activation of the EGF receptor,likely as a result of their clustering. We analyzed E-cadherin-EGFR interactions and their consequences in A431 cell and two colorectal cancer cell lines using immunobloting and analyzes of several protein kinases activities
  • In epithelial cells, the cell surface glycoprotein E-cadherin is a key molecule in the establishment of cell-cell adhesion. In addition to its contribution to cell adhesion, E-cadherin was found to induce ligand-independent activation of the EGF receptor,likely as a result of their clustering. We analyzed E-cadherin-EGFR interactions and their consequences in A431 cell and two colorectal cancer cell lines using immunobloting and analyzes of several protein kinases activities (en)
  • V epiteliálních buňkách je povrchový buněčný glykoprotein E-cadherin klíčovou molekulou při vzniku mezibuněčné adheze. Kromě jeho účasti na buněčné adhezi bylo zjištěno, že E-cadherin vyvolává aktivaci receptoru EGF nezávislou na ligandu, pravděpodobně jako výsledek jejich spojení. V buňkách A431 a ve dvou liniích buněk kolorektálního karcinomu jsme analyzovali vzájemné reakce E-cadherin-EGFR a jejich důsledky pomocí imunologického přenosu a analýzy aktivity řady protein-kináz (cs)
Title
  • Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells
  • Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells (en)
  • Transaktivace E-cadherinu se nepodílí na aktivitě receptoru EGF v buňkách kolorektálního karcinomu (cs)
skos:prefLabel
  • Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells
  • Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells (en)
  • Transaktivace E-cadherinu se nepodílí na aktivitě receptoru EGF v buňkách kolorektálního karcinomu (cs)
skos:notation
  • RIV/68378050:_____/04:00105294!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany
  • 1459;1464
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 590592
http://linked.open...ai/riv/idVysledku
  • RIV/68378050:_____/04:00105294
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • EGF receptor; E-cadherin; colorectal carcinoma cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GR - Řecká republika
http://linked.open...ontrolniKodProRIV
  • [22D5B04B6A26]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Oncology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 25
http://linked.open...iv/tvurceVysledku
  • Kučerová, Dana
  • Vojtěchová, Martina
  • Šloncová, Eva
  • Tuháčková, Zdena
  • Sovová, Vlasta
http://linked.open...n/vavai/riv/zamer
issn
  • 1019-6439
number of pages
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