About: Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1

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About: Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1 Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We immunobiochemically detected human seminal plasma proteins related to boar AQN 1 spermadhesin - hSA (human SpermAdhesin-like) proteins. In this study, we focused on further characterization of their 14kDa-, 16kDa- and 18kDa- forms (hSA-14, hSA 16 and hSA-18). Two hSA 14 isoforms interacted with heparin. Using indirect immunofluorescent microscopy, hSA protein epitopes were localized on the tail of human ejaculated sperm. On the basis of an ability of two isoforms of hSA proteins to interact with heparin and their localization on the sperm surface can be suggested that at least some of these proteins might be involved in sperm capacitation and fertilization in the human We immunobiochemically detected human seminal plasma proteins related to boar AQN 1 spermadhesin - hSA (human SpermAdhesin-like) proteins. In this study, we focused on further characterization of their 14kDa-, 16kDa- and 18kDa- forms (hSA-14, hSA 16 and hSA-18). Two hSA 14 isoforms interacted with heparin. Using indirect immunofluorescent microscopy, hSA protein epitopes were localized on the tail of human ejaculated sperm. On the basis of an ability of two isoforms of hSA proteins to interact with heparin and their localization on the sperm surface can be suggested that at least some of these proteins might be involved in sperm capacitation and fertilization in the human (en) Imunobiochemicky jsme určovali proteiny lidské semenné plazmy příbuzné kančímu spermadhezinu AQN 1 - proteiny hSA (human SpermAdhesin-like). V této studii jsme se zaměřili na další charakterizaci jejich forem o 14 kDa, 16 kDa a 18 kDa (hSA-14, hSA-16, hSA-18). Dvě izoformy hSA 14 reagovaly s heparinem. Pomocí nepřímé imunofluorescenční mikroskopie byly proteinové epitopy hSA lokalizovány na bičíku lidských ejakulovaných spermií. Na základě schopnosti obou izoforem proteinů hSA reagovat s heparinem a jejich lokalizaci na povrchu spermií lze vyvodit, že alespoň některé tyto proteiny by se mohly účastnit kapacitace spermií a oplodnění u člověka (cs)
Title	Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1 Charakterizace proteinů lidské semenné plazmy homologních s kančím spermadhezinem AQN 1 (cs) Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1 (en)
skos:prefLabel	Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1 Charakterizace proteinů lidské semenné plazmy homologních s kančím spermadhezinem AQN 1 (cs) Characterization of human seminal plasma proteins homologous to boar spermadhesin AQN 1 (en)
skos:notation	RIV/68378050:_____/04:00105279!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany	308
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA303/02/0433), P(GP303/02/P069), P(NJ7463), Z(AV0Z5052915)
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Jonáková, Věra Kraus, Marek
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	557401
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/04:00105279
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	human seminal plasma; spermadhesin; human ejaculated sperm (en)
http://linked.open.../riv/klicoveSlovo	human seminal plasma spermadhesin human ejaculated sperm
http://linked.open...ontrolniKodProRIV	[56FFECFB2D19]
http://linked.open...v/mistoKonaniAkce	Vancouver
http://linked.open...i/riv/mistoVydani	Madison
http://linked.open...i/riv/nazevZdroje	Biology of Reproduction
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of sperm surface proteins in the fertilization process Male infertility, sperm and seminal plasma status, damage biomarkers. Study of related proteins in seminal plasma of various mammalian species
http://linked.open...UplatneniVysledku	2004
http://linked.open...iv/tvurceVysledku	Jonáková, Věra Tichá, M. Kraus, Marek
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2004-08-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Society for the Study of Reproduction

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