About: Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells

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About: Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	V doménách pro vazbu na DNA a pro oligomerizaci genu TP53 byly detegovány četné delece v pozdních i časných in vitro pasážích kuřecí nádorové buněčné linie PR9692. Tato nádorová buněčná linie vykazuje imortalizovaný fenotyp a získala schopnost metastazovat, která je výjimečná v rámci našeho modelu nádorů vyvolaných v-src u kongenních kuřat. (cs) We have detected frequent deletions of variable length in both DNA-binding and oligomerization domains of the TP53 in the late as well as early in vitro passages of the chicken tumor cell line PR9692. This tumor cell line shows an immortal phenotype and acquires a metastatic potential that is unique in our experimental model of v-src-induced tumors in congenic chicken. We have detected frequent deletions of variable length in both DNA-binding and oligomerization domains of the TP53 in the late as well as early in vitro passages of the chicken tumor cell line PR9692. This tumor cell line shows an immortal phenotype and acquires a metastatic potential that is unique in our experimental model of v-src-induced tumors in congenic chicken. (en)
Title	Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells Delece ve vazebné doméně pro DNA genu TP53 u kuřecích buněk transformovaných v-src (cs) Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells (en)
skos:prefLabel	Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells Delece ve vazebné doméně pro DNA genu TP53 u kuřecích buněk transformovaných v-src (cs) Deletions in the DNA-binding domain of the TP53 gene in v-src-transformed chicken cells (en)
skos:notation	RIV/68378050:_____/04:00000219!RIV/2005/AV0/A23005/N
http://linked.open.../vavai/riv/strany	285;292
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/02/0407), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	8-9
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Plachý, Jiří Trtková, Kateřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	559667
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/04:00000219
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	avian; sarcoma; immortalization (en)
http://linked.open.../riv/klicoveSlovo	sarcoma avian immortalization
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A7EB2D2028A2]
http://linked.open...i/riv/nazevZdroje	In Vitro - Cellular and Developmental Biology. Animal Section
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	V-src oncogenes the dominant players in a hierarchy of events leading to cancer
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	40
http://linked.open...iv/tvurceVysledku	Plachý, Jiří Trtková, Kateřina
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	1071-2690
number of pages	8 (xsd:int)

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