About: Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16.

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About: Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Moderately immunogenic HPV16-associated tumours, MHC class I+ and class I-, were used to examine the adjuvant effects of IL-2 and dendritic cells for surgical therapy. It has been found that in both types of tumours recombinant IL-2 and IL-2 gene-modified vaccines substantially reduced the tumour recurrence rate and inhibited tumour growth. The dendritic cells were effective only in surgical therapy of MHC class I+ tumours. Moderately immunogenic HPV16-associated tumours, MHC class I+ and class I-, were used to examine the adjuvant effects of IL-2 and dendritic cells for surgical therapy. It has been found that in both types of tumours recombinant IL-2 and IL-2 gene-modified vaccines substantially reduced the tumour recurrence rate and inhibited tumour growth. The dendritic cells were effective only in surgical therapy of MHC class I+ tumours. (en)
Title	Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. (en)
skos:prefLabel	Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. (en)
skos:notation	RIV/68378050:_____/03:23033052!RIV/2004/GA0/A23004/N
http://linked.open.../vavai/riv/strany	891;896
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/00/0114), P(GA301/01/0985), P(IAA5052203), P(IAA7052002), P(NC7148), Z(AV0Z5052915)
http://linked.open...iv/cisloPeriodika	9-10
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Mendoza, Luis Mikyšková, Romana Šímová, Jana Bubeník, Jan Indrová, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	610923
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/03:23033052
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	interleukin-2; HPV 16; dendritic cells (en)
http://linked.open.../riv/klicoveSlovo	interleukin-2 dendritic cells HPV 16
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[CEB2F3EBA5DC]
http://linked.open...i/riv/nazevZdroje	Vaccine
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Dendritic cell based cancer vaccines Combined therapy of metastazising tumours induced by HPV 16 E8/E7 and ras oncogenes Tumour vaccines constructed by fusion of tumour and dendritic cells Gene therapy: vaccines based on the synergistic effect of genes regulating cooperation of dendritic cells and lymphocytes during tumour rejection Vaccination against two types (MHC I+ and MHC I-) of tumours induced by E6/E7 HPV16 viral oncogenes.
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Bubeník, Jan Indrová, Marie Mikyšková, Romana Šímová, Jana Šmahel, M. Vonka, V. Mendoza, Luis
http://linked.open...n/vavai/riv/zamer	Regulace a signální cesty uplatňující se v genové expresi, imunitě, onkogenezi, replikaci virů, tvorbě buněčných struktur, chování buněk, vývoji a oplození
issn	0264-410X
number of pages	6 (xsd:int)

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